Latest Diagnostic and Treatment Modalities for TTP

Latest Diagnostic and Treatment Modalities for TTP

Ali Ghani

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AliRaza Ghani

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Ahsan Raza

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ρ Lankenau Institiute of Medical Research

Latest Diagnostic and Treatment Modalities for TTP

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Abstract

TTP is a very uncommon disease which used to have very high mortality and morbidity before the introduction of plasmapharesis and immunosup-pressant therapy. Even after the introduction of these modalities, atypical HUS patients had a very grave prognosis and ultimately led to death in many until the introduction of complement inhibitors like eculizumab which is C5a monoclonal antibody. Additionally differentiating typical HUS versus atypical HUS was very difficult but some work on complement markers can be very fruitful in differentiating them.

References

18 Cites in Article

Reference Format

James George (2010). How I treat patients with thrombotic thrombocytopenic purpura: 2010.
M Scully,B Hunt,S Benjamin (2012). Guidelines on the diagnosis and management of thrombotic thromb-ocytopenic purpura and other thrombotic microan-giopathies.
Giuseppe Remuzzi,Serafino Garella (1987). HUS and TTP: Variable expression of a single entity.
Piero Ruggenenti,Marina Noris,Giuseppe Remuzzi (2001). Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura.
S Allford,B Hunt,P Rose (2003). Guidelines on the diagnosis and management of the thrombotic microangiopathichaemolyticanaemias.
H Tsai (2003). Advances in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura.
Gail Rock,Kenneth Shumak,Noel Buskard,Victor Blanchette,John Kelton,Rama Nair,Robert Spasoff (1991). Comparison of Plasma Exchange with Plasma Infusion in the Treatment of Thrombotic Thrombocytopenic Purpura.
Sara Vesely,James George,Bernhard Lämmle,Jan-Dirk Studt,Lorenzo Alberio,Mayez El-Harake,Gary Raskob (2003). ADAMTS13 activity in thrombotic thrombocytopenic purpura–hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients.
J Moake (2002). Thrombotic microangiopathies.
J Sadler (2008). Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura.
E Amorosi,J Ultmann (1966). Thrombotic thrombocytopenic purpura: Report of 16 cases and review of the literature.
Von Baeyer,H (2002). Plasmapheresis in thrombotic microangiopathy-associated syndromes: review of outcome data derived from clinical trials and open studies.
B Wyllie,A Garg,J Macnab,G Rock,W Clark (2006). Thrombotic thrombocytopenic purpura/haemolytic uraemic syndrome: a new index predicting response to plasma exchange.
Mini Michael,Elizabeth Elliott,Greta Ridley,Elisabeth Hodson,Jonathan Craig (2009). Interventions for haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura.
Kremer Hovinga,J Vesely,S Terrell,D (2010). Survival and relapse in patients with thrombotic thromboc-ytopenic purpura.
Samhar Al-Akash,P Almond,Van Savell,Salam Gharaybeh,Cris Hogue (2011). Eculizumab induces long-term remission in recurrent post-transplant HUS associated with C3 gene mutation.
J Jump Up^ Zuber,Le Quintrec,M Sberro-Soussan,R Loirat,C Frémeaux-Bacchi,V Legendre,C (2011). New insights into postrenal transplant hemolytic uremic syndrome.
Han-Mou Tsai (2010). Pathophysiology of thrombotic thrombocytopenic purpura.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Ali Ghani. 2014. \u201cLatest Diagnostic and Treatment Modalities for TTP\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 14 (GJMR Volume 14 Issue F3): .

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GJMR Volume 14 Issue F3
Pg. 11- 16

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

atypical hemolytic uremic syndrome complement factors eculizumab plasmapharesis Thrombotic thrombocytopenic purpura

Submission ReceivedDecember 7, 2013
Peer Review Double Blind
Handling Editor
Accepted January 4, 2014
Published January 15, 2014

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v1.2

Issue date

September 13, 2014

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Article Matrices

Total Score: 132

Country: United States

Subject: Global Journal of Medical Research - F: Diseases

Authors: AliRaza Ghani, Ahsan Raza (PhD/Dr. count: 0)

View Count (all-time): 163

Total Views (Real + Logic): 4593

Total Downloads (simulated): 2298

Publish Date: 2014 09, Sat

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Total Views: 4593

Total Downloads: 2298

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