Liver Damage in Pediatric Critically Ill COVID-19 Patients: Brazilian Case-Series

Liver Damage in Pediatric Critically Ill COVID-19 Patients: Brazilian Case-Series

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Werther Brunow De Carvalho

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Michele Luglio

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Uenis Tannuri

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Maria Fernanda Badue Pereira

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Isadora Souza Rodrigues

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Cintia Johnston

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Artur Figueiredo Delgado

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Universidade de São Paulo

Liver Damage in Pediatric Critically Ill COVID-19 Patients: Brazilian Case-Series

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Abstract

Coronavirus disease 2019 (COVID-19) has become an important cause critical care admission worldwide. In the context of newly described multisystem inflammatory syndrome temporally related to SARS-CoV-2 (PIM-TS), the question of liver compromise came into evidence. Our group summarized a case series of 6 critically ill COVID-19 pediatric patients that presented some degree of liver damage, as demonstrated by liver and/or canalicular enzymes elevation, a yet not fully explored characteristic of the infection in the pediatric patient, that may indicate a more severe progression. Observations regarding the role of systemic inflammatory response can be taken from the described cases.

References

14 Cites in Article

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

werther_brunow_de_carvalho. 2020. \u201cLiver Damage in Pediatric Critically Ill COVID-19 Patients: Brazilian Case-Series\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 20 (GJMR Volume 20 Issue F12).

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GJMR Volume 20 Issue F12

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification NLMC Code: WS 205

Submission ReceivedDecember 9, 2019
Peer Review Double Blind
Handling Editor
Accepted December 31, 2019
Published January 15, 2020

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v1.2

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December 14, 2020

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