Neural Networks and Rules-based Systems used to Find Rational and Scientific Correlations between being Here and Now with Afterlife Conditions
Neural Networks and Rules-based Systems used to Find Rational and
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As nature has selected amphibian skin defensive peptides for inter-species delivery through the oral route in the recipient, structural stabilisation modifications may have occurred to facilitate this and such information would be most useful and could potentially provide new insights to the design of orally-active and selectively-targeted peptide therapeutics. The purposes of this study were to study catabolic pathways in saliva for selected but commonly occurring bioactive peptide types belonging to the protease inhibitor (PI) and bradykinin-related peptide (BRP) families, namely pLR (LVRGCWTKS-YPPKPCFVR), HV-BBI (SVIGCWTKSIPPRPC FVK) and I-11-R (IRRPPGFSPLR), and to extend this study by determining catabolic pathways with kallikrein -the major salivary protease. These data will aid in the establishment of a database of peptide stabilities that may be useful in the design of future orally-delivered peptide therapeutics.
Xiaole Chen. 2016. \u201cMass Spectrometric Identification of Catabolic Pathways in the Selected Amphibian Skin Peptides With the Saliva and the Major Salivary Protease, Kallikrein\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 16 (GJMR Volume 16 Issue B2): .
Crossref Journal DOI 10.17406/gjmra
Print ISSN 0975-5888
e-ISSN 2249-4618
The methods for personal identification and authentication are no exception.
Total Score: 136
Country: China
Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine
Authors: Xiaole Chen, He Wang, Lei Wang, Mei Zhou, Tianbao Chen, Chris Shaw (PhD/Dr. count: 0)
View Count (all-time): 153
Total Views (Real + Logic): 3866
Total Downloads (simulated): 1754
Publish Date: 2016 08, Sat
Monthly Totals (Real + Logic):
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As nature has selected amphibian skin defensive peptides for inter-species delivery through the oral route in the recipient, structural stabilisation modifications may have occurred to facilitate this and such information would be most useful and could potentially provide new insights to the design of orally-active and selectively-targeted peptide therapeutics. The purposes of this study were to study catabolic pathways in saliva for selected but commonly occurring bioactive peptide types belonging to the protease inhibitor (PI) and bradykinin-related peptide (BRP) families, namely pLR (LVRGCWTKS-YPPKPCFVR), HV-BBI (SVIGCWTKSIPPRPC FVK) and I-11-R (IRRPPGFSPLR), and to extend this study by determining catabolic pathways with kallikrein -the major salivary protease. These data will aid in the establishment of a database of peptide stabilities that may be useful in the design of future orally-delivered peptide therapeutics.
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