Melatonin to Reduce Death Toll Due to COVID-19: From Innate to Adaptive Immune Response

Jan Tesarik

Melatonin to Reduce Death Toll Due to COVID-19: From Innate to Adaptive Immune Response

Jan Tesarik *

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Melatonin to Reduce Death Toll Due to COVID-19: From Innate to Adaptive Immune Response

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Abstract

This paper highlights a new, nonspecific medication, which could be used both as a preventive and a curative measure to slow down the progression of Coronavirus disease 2019 (COVID-19) until a more specific treatment is available. The suggested treatment (immunomodulation) consists in the administration of melatonin, a substance shown to inhibit the innate (blind and usually harmful) immune response while facilitating the adaptive one, the only capable of fighting efficiently against the infection. In low oral doses, melatonin can be administered preventively to persons at risk and those already infected but still asymptomatic. High, intravenously administered doses may help critical patients under imminent threat of death. The combined use of both strategies will hopefully unblock the current overcharge of intensive care units by reducing new admissions and favoring healed patient discharge.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Jan Tesarik. 2020. "Melatonin to Reduce Death Toll Due to COVID-19: From Innate to Adaptive Immune Response". Global Journal of Medical Research - K: Interdisciplinary GJMR-K Volume 20 (GJMR Volume 20 Issue K8).

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GJMR Volume 20 Issue K8

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

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Classification

GJMR-K Classification NLMC Code: QW 640

Submission ReceivedDecember 15, 2019
Peer Review Double Blind
Handling Editor
Accepted January 3, 2020
Published January 15, 2020

Version of record

v1.2

Issue date

July 31, 2020

Language

English

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