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Many oral anti-hyperglycemic agents have been used for treatment of Type II diabetes (TY2D), yet Metformin, the only compound remained of biguanide derivates, continued to be used in this treatment. Its mechanism of action and pharmacokinetics are unique and significant. It has low side effects and no adverse incidences with healthy heart and kidney T2D, compared with its family group members. The previous properties made metformin tops the oral anti hyperglycemic agents list recommended from FDA in TY2D therapy. In this review paper, we aimed to point at bi-guanide development through time as glucose lowering agents, and show the magnificent characteristics of dimethylbiguanide; metformin.
Farah Yousef. 2017. \u201cMetformin: A Unique Herbal Origin Medication\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 17 (GJMR Volume 17 Issue B3): .
Crossref Journal DOI 10.17406/gjmra
Print ISSN 0975-5888
e-ISSN 2249-4618
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Total Score: 104
Country: Unknown
Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine
Authors: Farah Yousef, Nadin Yousef, Oussama Mansour, Jehad Herbali (PhD/Dr. count: 0)
View Count (all-time): 154
Total Views (Real + Logic): 3232
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Publish Date: 2017 11, Fri
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Many oral anti-hyperglycemic agents have been used for treatment of Type II diabetes (TY2D), yet Metformin, the only compound remained of biguanide derivates, continued to be used in this treatment. Its mechanism of action and pharmacokinetics are unique and significant. It has low side effects and no adverse incidences with healthy heart and kidney T2D, compared with its family group members. The previous properties made metformin tops the oral anti hyperglycemic agents list recommended from FDA in TY2D therapy. In this review paper, we aimed to point at bi-guanide development through time as glucose lowering agents, and show the magnificent characteristics of dimethylbiguanide; metformin.
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