Molecular Typing of HLA B27 in UVEITIS Patients at a Tertiry Care Centre in India and its Clinical Implications

Molecular Typing of HLA B27 in UVEITIS Patients at a Tertiry Care Centre in India and its Clinical Implications

Indu Yadav

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Indrani Dhawan

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Guru Gobind Singh Indraprastha University

Molecular Typing of HLA B27 in UVEITIS Patients at a Tertiry Care Centre in India and its Clinical Implications

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Abstract

Uveitis is a common ocular disease characterized by inflammation of iris, choroid, and ciliary body. HLA-B27 is the strongest known genetic risk factor for acute anterior uveitis. The prevalence of HLA B27 and associated diseases varies widely across different racial groups and have massive clinical implications. DNA typing was done using amplification of genomic DNA by the polymerase chain reaction (PCR) and hybridization with sequence-specific oligonucleotide probes (SSOP). This study was undertaken due to paucity of recent reports on Asian Indian population with uveitis as a predominant clinical feature.

References

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Indu Yadav. 2019. \u201cMolecular Typing of HLA B27 in UVEITIS Patients at a Tertiry Care Centre in India and its Clinical Implications\u201d. Global Journal of Medical Research - C: Microbiology & Pathology GJMR-C Volume 19 (GJMR Volume 19 Issue C2): .

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GJMR Volume 19 Issue C2
Pg. 7- 10

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-C Classification: NLMC Code: QZ 4

Submission ReceivedDecember 11, 2018
Peer Review Double Blind
Handling Editor
Accepted January 2, 2019
Published January 15, 2019

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December 14, 2019

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