Natural Antioxidants and their Intrinsic Worth for Wellbeing

Natural Antioxidants and their Intrinsic Worth for Wellbeing

Bina Rani

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Raaz K Maheshwari

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α Rajasthan Technical University

σ Maharshi Dayanand Saraswati University

Natural Antioxidants and their Intrinsic Worth for Wellbeing

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Abstract

Free radicals produced on exposure to sunlight, X-rays, ozone, tobacco smoke, automobile exhaust, environmental pollutants, and by several other physiological processes, are highly reactive and can damage nucleic acids, proteins, lipids and carbohydrates that subsequently affect the immune functioning causing degenerative diseases. In a normal cell there is an appropriate balance between prooxidant and antioxidants. When the level of pro-oxidants is increased in comparison to antioxidant, this state is termed as oxidative stress (OS). It is imposed on the cells due to increase in oxidant generation and decrease in antioxidants protection, resulting in failure in repair of oxidative damage. Exposure to pathogens, inappropriate lifestyle, excessive exercise, and by-products of normal metabolism are also contributing factors to OS. Reactive oxygen species are also responsible for DNA (deoxyribose nucleic acid) damages resulting in mutagenic changes that are responsible for several diseases. Oxidative stress deregulates the cellular functions leading to neuro-degenerative diseases, gastroduodenal pathogenesis, some kinds of cancer, cataracts, premature aging, inflammation, cardiovascular, and metabolic dysfunction.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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How to Cite This Article

Bina Rani. 2014. \u201cNatural Antioxidants and their Intrinsic Worth for Wellbeing\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 13 (GJMR Volume 13 Issue B7): .

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GJMR Volume 13 Issue B7
Pg. 53- 69

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

allicin epidemiological data genestein glucomannans nutritive value pdcaasw peroxidation phytochemicals RDA ROS: free radicals

Submission ReceivedDecember 16, 2012
Peer Review Double Blind
Handling Editor
Accepted January 1, 2013
Published January 15, 2013

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February 12, 2014

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Article Matrices

Total Score: 102

Country: India

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Bina Rani, Raaz K Maheshwari (PhD/Dr. count: 0)

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