Origanum vulgare (oregano) and its Carvacrol Biocomponent as an Alternative of Antimicrobial Agent

1
Natalia Kaori Aida
Natalia Kaori Aida
2
Janaina Priscila Barbosa
Janaina Priscila Barbosa
3
Thais Rossini de Oliveira
Thais Rossini de Oliveira
4
Vanessa da Silva Cardoso
Vanessa da Silva Cardoso
5
Simone Nataly Busato de Feiria
Simone Nataly Busato de Feiria
6
Giovana Claudia Boni
Giovana Claudia Boni
7
Jose Francisco Hofling
Jose Francisco Hofling

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The use of plants as an alternative to medicinal treatments is an old practice. The increased resistance of microorganisms to conventional antimicrobials has made studies with medicinal plants increasingly relevant, and ethnobotanical and ethnopharmacological knowledge is considered essential for the development of new drugs. The essential oil of Origanum vulgare and its isolated compound Carvacrol have antimicrobial effects demonstrated in the literature as antibacterial and antifungal activity. Therefore, the present study evaluated the antibacterial and antifungal activity of O. vulgare and Carvacrol using the broth microdilution method (CLSI, 2008), determining MIC (Minimum Inhibitory Concentration) and MFC and MBC (Minimum Fungicidal Concentration and Concentration Minimum Bactericide). Used as standard comparative the antimicrobials Fluconazoleand Chlorhexidine.

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Natalia Kaori Aida. 2020. \u201cOriganum vulgare (oregano) and its Carvacrol Biocomponent as an Alternative of Antimicrobial Agent\u201d. Global Journal of Medical Research - C: Microbiology & Pathology GJMR-C Volume 20 (GJMR Volume 20 Issue C3): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-C Classification: NLMC Code: QW 4
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July 17, 2020

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English

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The use of plants as an alternative to medicinal treatments is an old practice. The increased resistance of microorganisms to conventional antimicrobials has made studies with medicinal plants increasingly relevant, and ethnobotanical and ethnopharmacological knowledge is considered essential for the development of new drugs. The essential oil of Origanum vulgare and its isolated compound Carvacrol have antimicrobial effects demonstrated in the literature as antibacterial and antifungal activity. Therefore, the present study evaluated the antibacterial and antifungal activity of O. vulgare and Carvacrol using the broth microdilution method (CLSI, 2008), determining MIC (Minimum Inhibitory Concentration) and MFC and MBC (Minimum Fungicidal Concentration and Concentration Minimum Bactericide). Used as standard comparative the antimicrobials Fluconazoleand Chlorhexidine.

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Origanum vulgare (oregano) and its Carvacrol Biocomponent as an Alternative of Antimicrobial Agent

Natalia Kaori Aida
Natalia Kaori Aida
Janaina Priscila Barbosa
Janaina Priscila Barbosa
Thais Rossini de Oliveira
Thais Rossini de Oliveira
Vanessa da Silva Cardoso
Vanessa da Silva Cardoso
Simone Nataly Busato de Feiria
Simone Nataly Busato de Feiria
Giovana Claudia Boni
Giovana Claudia Boni
Jose Francisco Hofling
Jose Francisco Hofling

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