Oxidative Stress in Dogs in Different Stages of Chronic Kidney Disease

Andre B. Galvao

Oxidative Stress in Dogs in Different Stages of Chronic Kidney Disease

Andre B. Galvao *

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Oxidative Stress in Dogs in Different Stages of Chronic Kidney Disease

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Abstract

The objective of this study to quantify oxidative stress in dogs with naturally acquied chronic kidney disease (CKD), considering the four stages of disease progression, using as markers reactive substances to thiobarbituric acid. Five groups of dogs, all aged between four to 18 years old. Were studied the control group was composed of healthy animals (CG, n = 17), CKD stage 1 group (CKD-1, n = 12), CKD stage 2 group (CKD-2, n = 10), CKD stage 3 group (CKD-3, n = 13) and CKD stage 4 group (CKD-4, n = 10). Oxidative stress was measured by antioxidante power, using as markers reactive substances to thiobarbituric acid. Data (means of duplicates) were submitted to analysis of variance (One-way ANOVA) nonparametric (Kruskal-Wallis) (α =0.05). The results were expressed as mean±standard error of the mean. The serumcreatinine values guided the classification of patients as CG, CKD-1, CKD-2, CKD-3 and CKD-4 andwere 1.02±0.02 mg/dL, 1.06±0.05 mg/dL, 1.80±0.03 mg/dL, 3.39±0.21 mg/dL and 6.00±0.28 mg/dL, respectively. The results related to antioxidant power (GC) 0.032±0.002 mmol/μL, (CKD-1) 0.030±0.002 nmol/μL, (CKD-2) 0.028±0.003 nmol/μL, (CKD-3) 0.027±0.003 nmol/μL and (CKD-4) 0.025 ± 0.002 nmol/μL.

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18 Cites in Article

Reference Format

K Barbosa,N Costa,R Alfenas,S De Paula,V Minim,J Bressan (2010). Estresse oxidativo: conceito, implicações e fatores modulatórios.
John Buege,Steven Aust (1978). [30] Microsomal lipid peroxidation.
Victoria Cachofeiro,Marian Goicochea,Soledad De Vinuesa,Pilar Oubiña,Vicente Lahera,José Luño (2008). Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease.
M Carvalho,L Feitosa (2014). Semiologia do sistema urinário.
Lesley Rees (2013). Vitamin D levels in chronic kidney disease (CKD).
J Galvão,L Nagode,P Schenck,D Chew (2013). Calcitriol, calcidiol, parathyroid hormone, and fibroblast growth factor-23 interactions in chronic kidney disease.
Ioannis Karamouzis,Pantelis Sarafidis,Michael Karamouzis,Stavros Iliadis,Anna-Bettina Haidich,Athanasios Sioulis,Athanasios Triantos,Norma Vavatsi-Christaki,Dimitrios Grekas (2008). Increase in Oxidative Stress but Not in Antioxidant Capacity with Advancing Stages of Chronic Kidney Disease.
F Locatelli,B Canaud,K Eckardt,P Stenvinkel,C Wanner,C Zoccatli (2003). Oxidative stress in end-stage renal disease: an emerging threat to pacient outcome.
M Lustoza (2004). Avaliação do estresse oxidativo em cães com insuficiência renal crônica e anemia.
Anderson Souza,Milena Granella,Paula Tokawa,Stefano Hagen (2004). Guia de posicionamento radiográfico em equinos.
Pedro Cardoso,Simone Balian (2005). Manual técnico de controle sanitário para peixes ornamentais: criação e implementação de programas de autocontrole com base no sistema APPCC.
Miguel Payá,Barry Halliwell,J Hoult (1992). Interactions of a series of coumarins with reactive oxygen species.
H Schmid,H Schiffl (2010). Erythropoiesis stimulating agents and anaemia of end-stage renal disease.
A Scoot (2008). Oxidative stress and chronic kidney disease.
David Small,Jeff Coombes,Nigel Bennett,David Johnson,Glenda Gobe (2012). Oxidative stress, anti‐oxidant therapies and chronic kidney disease.
Sandra Vasconcelos,Marília Goulart,José Moura,Vanusa Manfredini,Mara Benfato,Lauro Kubota (2007). Espécies reativas de oxigênio e de nitrogênio, antioxidantes e marcadores de dano oxidativo em sangue humano: principais métodos analíticos para sua determinação.
C Urso,G Caimi (2011). Oxidative stress and endothelialdys function.
R Zatz,A Seguro,G Malnic (2012). Bases Fisiológicas da Nefrologia.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Andre Galvao. 2018. "Oxidative Stress in Dogs in Different Stages of Chronic Kidney Disease". Global Journal of Medical Research, Global Journal of Medical Research - G: Veterinary Science & Medicine GJMR-G Volume 18 (GJMR Volume 18 Issue G1).

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GJMR Volume 18 Issue G1

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

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Classification

GJMR-G Classification NLMC Code: WA 360

Submission ReceivedDecember 14, 2017
Peer Review Double Blind
Handling Editor
Accepted January 5, 2018
Published January 15, 2018

Version of record

v1.2

Issue date

June 6, 2018

Language

Portuguese

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Article Matrices

Total Score: 146

Country: Brazil

Subject: Global Journal of Medical Research

Authors: Andre B. Galvao, Marileda B. Carvalho, Luciane G. Batalho, Juliana C.B. Silva, Marcelo Batalho, Evelin C. Carnio (PhD/Dr. count: 0)

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