Part –III: Utilities of Active Methylene Compounds and Heterocycles Bearing Active Methyl or having an Active Methine in the Formation of  Substituted and Fused Pyridines

Part –III: Utilities of Active Methylene Compounds and Heterocycles Bearing Active Methyl or having an Active Methine in the Formation of Substituted and Fused Pyridines

Mohamed Abdel-Megid

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Ain Shams University

Part –III: Utilities of Active Methylene Compounds and Heterocycles Bearing Active Methyl or having an Active Methine in the Formation of Substituted and Fused Pyridines

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Abstract

This review discusses how we use the most common and novel synthesized active methylene compounds as well as heterocycles having active methyl or methine in the syntheses of a wide variety of substituted and fused pyridines interesting medical and pharmaceutical importance. Many synthetic approaches were used for the preparation of target heterocyclic systems such as cyclocondensation reactions, ring opening-ring closure, cycloaddition, acid-or base-catalyzed reaction, intermolecular cyclization and self-condensation have been reviewed in this paper. Also, the antimicrobial activity carried out on some newly selected synthesized pyridines and their fused derivatives were reported.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Mohamed Abdel-Megid. 2026. \u201cPart –III: Utilities of Active Methylene Compounds and Heterocycles Bearing Active Methyl or having an Active Methine in the Formation of Substituted and Fused Pyridines\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 22 (GJSFR Volume 22 Issue B1): .

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GJSFR Volume 22 Issue B1
Pg. 19- 36

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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Classification

GJSFR-B Classification: LCC Code: E487

Submission ReceivedJune 2, 2022
Peer Review Double Blind
Handling Editor
Accepted June 10, 2022
Published December 30, 2022

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v1.2

Issue date

January 14, 2023

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