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Asplenium ceterach is a fern used in traditional medicine against kidney stones and as a diuretic agent. Thus, we set as objective of this study is the determination of the phenolic profile as well as the study of anti-inflammatory and diuretic properties of Asplenium ceterach (Rustyback). Phenolic composition is achieved by High-performance liquid chromatography, the anti-inflammatory activity is determined in albino mice, and the diuretic activity in Wistar albino rats. The results of phenolic profile show an overall concentration of 3926 μg/g DM of Asplenium ceterach, of which 3/4 are represented by chlorogenic acid. This plant is endowed with an interesting plantar anti-inflammatory property and a topical anti-inflammatory comparable to that of ibuprofen. Asplenium ceterach expresses an excellent diuretic activity significantly higher that of Furosemide. This study confirms the traditional use of the infusion of Asplenium ceterach as a powerful diuretic and an anti-inflammatory.
Mostapha Bachir bey. 2020. \u201cPhenolic Profile, Anti-Inflammatory and Diuretic Properties of Asplenium Ceterach Tested on Albino Mice and Wistar Albino Rats\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 20 (GJMR Volume 20 Issue B6): .
Crossref Journal DOI 10.17406/gjmra
Print ISSN 0975-5888
e-ISSN 2249-4618
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Total Score: 105
Country: Algeria
Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine
Authors: Mostapha Bachir bey, Rekia Sidhoum, Latifa Halli, Othmane Yalaoui, Asma Belkadi (PhD/Dr. count: 0)
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Publish Date: 2020 08, Wed
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Asplenium ceterach is a fern used in traditional medicine against kidney stones and as a diuretic agent. Thus, we set as objective of this study is the determination of the phenolic profile as well as the study of anti-inflammatory and diuretic properties of Asplenium ceterach (Rustyback). Phenolic composition is achieved by High-performance liquid chromatography, the anti-inflammatory activity is determined in albino mice, and the diuretic activity in Wistar albino rats. The results of phenolic profile show an overall concentration of 3926 μg/g DM of Asplenium ceterach, of which 3/4 are represented by chlorogenic acid. This plant is endowed with an interesting plantar anti-inflammatory property and a topical anti-inflammatory comparable to that of ibuprofen. Asplenium ceterach expresses an excellent diuretic activity significantly higher that of Furosemide. This study confirms the traditional use of the infusion of Asplenium ceterach as a powerful diuretic and an anti-inflammatory.
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