Phyto-Melatonin and Immunity: A Review

Phyto-Melatonin and Immunity: A Review

Ghosh S

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Jai Prakash University

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Abstract

The basic structure of melatonin is evolutionarily conserved. Hence, it was speculated that melatonin may be present in different animals (from unicellular to multi-cellular) and even in plants. Melatonin in plans is generally regarded as phyto-melatonin. Like the role of melatonin in animals, phyto-melatonin can perform a number of functions like attenuation of apoptosis, prevention of free radical generation, protection against UV irradiation etc. But, unlike phytoestrogen, the role of phyto-melatonin in animals is totally an unexplored area. Hence, aim of the present study was to note the role of phyto-melatonin in maintenance of general health and immunity of goats. To fulfil the aim, we supplemented the goats with phyto-melatonin rich diet i.e. corn (Zea mays) which is having 1.4 ng/gm of dry weight of tissue and they are also edible to goats. We noted significantly high level of body weight, haematological (AST, ALT level, total RBC count and %Hb), immunological (TLC, %LC, %SR of PBMCs), metabolic (plasma glucose, cholesterol, HDL, LDL, protein levels and HDL: LDL ration), free radical (SOD, catalase, GPx levels), hormonal (estrogen, melatonin), cytokine (IL-6 and TNF-α) levels and significantly low level of MDA.

References

29 Cites in Article

Reference Format

R Ahmad,C Haldar (2010). Melatonin and androgen receptor expression interplay modulates cellmediated immunity in tropical rodent Funambulus pennanti: an in-vivo and in-vitro study.
F Badria (2002). Melatonin, serotonin, and tryptamine in some Egyptian food and medicinal plants.
Ivonne Balzer,Britta Höcker,Holger Kapp,Birgit Bartolomaeus (1998). Occurrence and comparative physiology of melatonin in evolutionary diverse organisms.
J Bruning,B Knitz (1977). Computational handbook of statistics.
B Calippe,V Douin-Echinard,M Laffargue (2008). Chronic estradiol administration in vivopromotes the proinûammatory response of macrophages to TLR4 activation: involvement of the phosphatidylinositol 3kinase pathway.
Antonio Carrillo-Vico,Patricia Lardone,Nuria Álvarez-Sánchez,Ana Rodríguez-Rodríguez,Juan Guerrero (2013). Melatonin: Buffering the Immune System.
S Chowdhury,M Bhuiyan,S Faruk (2002). Rearing Black Bengal Goat under Semi-Intensive Management 1. Physiological and Reproductive Performances.
K Das,Samanta,Gbn Chainy (2000). A modified spectrophotometric assay of superoxide dismutase using nitrite formation by superoxide radicals.
R Dubbels,R Reiter,E Klenke,A Goebel,Schnakenberg,C Ehlers (1995). Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography-mass spectrometry.
Paulino Fandos,Jorge Orueta,Yolanda Aranda (1993). Tooth wear and its relation to kind of food: The repercussion on age criteria in Capra pyrenaica.
Somenath Ghosh,Amaresh Singh,Chandana Haldar (2014). Seasonal modulation of immunity by melatonin and gonadal steroids in a short day breeder goat Capra hircus.
Chandana Haldar,Seema Rai,Rajesh Singh (2004). Melatonin blocks dexamethasone-induced immunosuppression in a seasonally breeding rodent Indian palm squirrel, Funambulus pennanti.
Rüdiger Hardeland,Burkhard Poeggeler (2003). Non‐vertebrate melatonin.
Josefa Hern�ndez-Ruiz,Antonio Cano,Marino Arnao (2004). Melatonin: a growth-stimulating compound present in lupin tissues.
J Kola´r,I Macha´ckova´ (2001). Occurrence and possible function of melatonin in plants, A review.
X Lei,Zhu,Ry,Zhang,Y Dai (2004). Attenuation of cold induced apoptosis by exogenous melatonin in carrot suspension cells: the possible involvement of polyamines.
M Lorenz,K Lu¨ning (1998). Detection of endogenous melatonin in the marine red macroalgae Porphyra umbilicalis and Palmaria palmata by enzyme-linked immunoassay (ELISA) and effects of melatonin administration on algal growth.
Subrahmanyam Mantha,Marion Prasad,Jawahar Kalra,Kailash Prasad (1993). Antioxidant enzymes in hypercholesterolemia and effects of vitamin E in rabbits.
U Mueller,R Hardeland (1999). Transient accumulations of exogenous melatonin indicate binding sites in the dinoflagellate Gonyaulax polyedra.
H Ohkawa,N Ohishi,K Yagi (1978). Reaction of linoleic acid hydroperoxide with thiobarbituric acid..
J Pauly,Sokal,T Han (1973). Whole-blood culture technique for functional studies of lymphocyte reactivity to mitogens, antigens, and homologous lymphocytes.
Małgorzata Posmyk,Hanna Kuran,Kazimierz Marciniak,Krystyna Janas (2008). Presowing seed treatment with melatonin protects red cabbage seedlings against toxic copper ion concentrations.
Russel Reiter,Dun-Xian Tan,Lucien Manchester,Artemis Simopoulos,Maria Maldonado,Luis Flores,M Terron (2007). Melatonin in Edible Plants (Phytomelatonin): Identification, Concentrations, Bioavailability and Proposed Functions.
David Sackett,Epidemiology (1969). CLINICAL EPIDEMIOLOGY.
Shweta Sharma,Chandana Haldar,Shail Chaube (2008). Effect of exogenous melatonin on X-ray induced cellular toxicity in lymphatic tissue of Indian tropical male squirrel,Funambulus pennanti.
Asru Sinha (1972). Colorimetric assay of catalase.
Dun‐xian Tan,Lucien Manchester,Paolo Di Mascio,Glaucia Martinez,Fernanda Prado,Russel Reiter (2007). Novel rhythms of N 1 ‐acetyl‐N 2 ‐formyl‐5‐methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation.
C Tettamanti,B Cerabolini,Gerola,A Conti (2000). Melatonin identification in medicinal plants.
Jirasak Wong-Ekkabut,Zhitao Xu,Wannapong Triampo,I-M Tang,D Peter Tieleman,Luca Monticelli (2007). Effect of Lipid Peroxidation on the Properties of Lipid Bilayers: A Molecular Dynamics Study.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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How to Cite This Article

Ghosh S. 2021. \u201cPhyto-Melatonin and Immunity: A Review\u201d. Global Journal of Science Frontier Research - C: Biological Science GJSFR-C Volume 21 (GJSFR Volume 21 Issue C4).

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GJSFR Volume 21 Issue C4

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Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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GJSFR-C Classification FOR Code: 069999

Submission ReceivedJune 30, 2021
Peer Review Double Blind
Handling Editor
Accepted July 23, 2021
Published August 7, 2021

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v1.2

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October 4, 2021

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