Phytochemical and Therapeutic Studies of the Fruit Essential Oil of Thujaorientalis from Nigeria

Ololade Z.S.; Sunday Ololade

Phytochemical and Therapeutic Studies of the Fruit Essential Oil of Thujaorientalis from Nigeria

Ololade Z.S. * §

Contact

Sunday Ololade ‡

Contact

§ Bells University of Technology

‡ Ladoke Akintola University of Technology

Phytochemical and Therapeutic Studies of the Fruit Essential Oil of Thujaorientalis from Nigeria

Article Fingerprint

ReserarchID

7MT93

Phytochemical and Therapeutic Studies of the Fruit Essential Oil of Thujaorientalis from Nigeria Banner

Key Research Insights

Synthesized scholarly intelligence & interactive research assistant

This converted HTML version may contain rendering inconsistencies. Please refer to the PDF for the authoritative version, or click here to provide feedback.

Abstract

The aim of this study was to establish correlations between the identified phytocompounds in the fruit essential oil of Thuja orientalis from Nigeria and their medicinal properties (free radical scavenging, antioxidant and antimicrobial). Forty-seven compounds were identified in the fruit essential oil of T. orientalis making up 97.5% of the total percentage composition. The essential oil was predominantly made up of monoterpenoids (62.2%). The most abundant components was 1R-α-pinene (15.2%) followed by α-pinene (9.6%), 1S-α-pinene (5.6%), cyclofenchene (5.6%), (+)-3-carene (4.5%), DL-pinene (4.5%) and trans-β-ocimene (4.0%). The high amount of terpenoids leads to more potent radical scavenging, antioxidant and antibiotic properties. The essential oil showed high potential as natural antioxidant and free radical inhibitor with IC50 value: 2.5μgml-1, the percentage inhibition of free radical ranged between 68-70%. Screening of the fruit essential oil for antimicrobial activities using the agar-well diffusion assay showed that the oil had high antibacterial properties against all bacteria isolates tested with zones of inhibition ranging from 10-30 mm.

References

17 Cites in Article

Reference Format

1. P Angienda,D Onyango,D Hill (2010). Potential application of plant essential oils at sub-lethal concentrations under extrinsic conditions that enhance their antimicrobial effectiveness against pathogenic bacteria. African Journal of Microbiology Research, 4(16), 1678-1684.
2. G Buchbauer (2000). The detailed analysis of essential leads to the understanding of their properties. Perfumer flavorist, 25, 64-67.
3. S Das,Rani (2013). Antioxidant and gastroprotective properties of the fruits of Thujaoccidentalis Linn. Asian Journal of Biochemical and Pharmaceutical Research, 3(3), 80-87.
4. S Dubey (2009). Antioxidant Activities of Thuja Occidentalis Linn. Asian Journal of Pharmaceutical and Clinical Research, 2(1), 73-76.
5. (2004). European Pharmacopoeia Commission. European Pharmacopoeia 5th. European Pharmacopoeia Commission. European Pharmacopoeia 5th
6. A Hamid,O Aiyelaagbe,L Usman,O Ameen,A Lawal (2010). Antioxidants: Its medicinal and pharmacological applications. African Journal of Pure and Applied Chemistry, 4(8), 142-151.
7. H Ibrahim,I Imam,A Bello,U Umar,S Muhammad,S Abdullahi (2012). The Potential of Nigerian Medicinal Plants as Antimalarial Agent: A Review. International Journal of Science and Technology, 2(8), 600-605.
8. L Jirovetz,G Buchbauer,Z Denkova,A Slavchev,A Stoyanova,E Schmidt (2006). Chemical composition, antimicrobial activities and odour descriptions of various Salvia sp. and Thuja sp. essential oils. Ernahrung/Nutrition, 30, 4.
9. Rbq Pimentel,C Costa,P Albuquerque,S Junior (2013). Antimicrobial activity and rutin identification of honey produced by the stingless bee Meliponacompressipesmanaosensis and honey. BMC Complementary and Medicine, 13(151), 1-14.
10. L Pham-Huy,H He,C Pham-Huy (2008). Free Radicals, Antioxidants in Disease and Health. Int. J. Biomed. Sci, 4(2), 89-96.
11. Ronald Prior,Xianli Wu,Karen Schaich (2005). Standardized Methods for the Determination of Antioxidant Capacity and Phenolics in Foods and Dietary Supplements. Journal of Agricultural and Food Chemistry, 53(10), 4290-4302.
12. Savithramman,M Rao,D Suhrulatha (2011). Screening of Medicinal Plants for Secondary Metabolites. Middle-East Journal of Scientific Research, 8(3), 579-584.
13. Syed Shah,Abdul Sadiq,Syed Shah,Farhat Ullah (2014). Antioxidant, total phenolic contents and antinociceptive potential of Teucrium stocksianum methanolic extract in different animal models. BMC Complementary and Alternative Medicine, 14(1), 1-14.
14. D Tsiri,K Graikou,L Pobłocka-Olech,M Krauze-Baranowska,C Spyropoulos,I Chinou (2009). Chemosystematic Value of the Essential Oil Composition of Thuja species Cultivated in Poland-Antimicrobial Activity. Molecules, 14, 4707-4715.
15. Afaf Weli,Sabha Al-Hinai,Mohammad Hossain,Jamal Al-Sabahi (2014). Composition of essential oil of OmaniJuniperus excelsafruit and antimicrobial activity against foodborne pathogenic bacteria. Journal of Taibah University for Science, 8(3), 225-230.
16. X Zhang,Y Choe,Y Park,B Kim Effect of Korean arbor vitae (Thuja koraiensis) extract on. Effect of Korean arbor vitae (Thuja koraiensis) extract on
17. Zeynep Baharoglu,Geneviève Garriss,Didier Mazel (2013). Multiple Pathways of Genome Plasticity Leading to Development of Antibiotic Resistance. Antibiotics, 2(2), 288-315.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Ololade Z.S., Sunday Ololade. 2015. "Phytochemical and Therapeutic Studies of the Fruit Essential Oil of Thujaorientalis from Nigeria". Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 14 (GJSFR Volume 14 Issue B7).

More Citation Formats

Select Citation Style:

Download Citation

GJSFR Volume 14 Issue B7

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

antibacterial antioxidant fruit essential oil Phytochemical Thuja orientalis

Classification

GJSFR-C Classification FOR Code: 780105p

Submission ReceivedNovember 3, 2014
Peer Review Double Blind
Handling Editor
Accepted November 23, 2014
Published December 7, 2014

Version of record

v1.2

Issue date

January 5, 2015

Language

English

Order Article Reprint

Experience in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Score: 105

Country: Nigeria

Subject: Global Journal of Science Frontier Research - B: Chemistry

Authors: Ololade Z.S., Fakankun O.A., Alao, F.O., Udi O.U. (PhD/Dr. count: 0)

View Count (all-time): 386

Total Views (Real + Logic): 869

Total Downloads (simulated): 66

Publish Date: 2014 12, Sun

Monthly Totals (Real + Logic):

Month 1: 56 views
Month 2: 55 views
Month 3: 45 views
Month 4: 54 views
Month 5: 38 views
Month 6: 44 views
Month 7: 41 views
Month 8: 38 views
Month 9: 50 views
Month 10: 56 views
Month 11: 42 views
Month 12: 39 views
Month 13: 13 views
Month 14: 31 views
Month 15: 33 views
Month 16: 33 views
Month 17: 26 views
Month 18: 44 views
Month 19: 23 views
Month 20: 31 views
Month 21: 32 views
Month 22: 24 views
Month 23: 18 views
Month 24: 22 views
Month 25: 33 views
Month 26: 27 views
Month 27: 30 views
Month 28: 17 views
Month 29: 46 views
Month 30: 26 views
Month 31: 35 views
Month 32: 24 views
Month 33: 14 views
Month 34: 29 views
Month 35: 43 views
Month 36: 26 views
Month 37: 27 views
Month 38: 16 views
Month 39: 40 views
Month 40: 19 views
Month 41: 25 views
Month 42: 20 views
Month 43: 15 views
Month 44: 21 views
Month 45: 40 views
Month 46: 34 views
Month 47: 18 views
Month 48: 22 views
Month 49: 29 views
Month 50: 12 views
Month 51: 33 views
Month 52: 20 views
Month 53: 38 views
Month 54: 36 views
Month 55: 30 views
Month 56: 26 views
Month 57: 31 views
Month 58: 36 views
Month 59: 27 views
Month 60: 45 views
Month 61: 14 views
Month 62: 40 views
Month 63: 30 views
Month 64: 38 views
Month 65: 20 views
Month 66: 22 views
Month 67: 16 views
Month 68: 38 views
Month 69: 22 views
Month 70: 24 views
Month 71: 42 views
Month 72: 27 views
Month 73: 38 views
Month 74: 37 views
Month 75: 24 views
Month 76: 25 views
Month 77: 48 views
Month 78: 35 views
Month 79: 43 views
Month 80: 32 views
Month 81: 34 views
Month 82: 20 views
Month 83: 23 views
Month 84: 30 views
Month 85: 17 views
Month 86: 37 views
Month 87: 18 views
Month 88: 39 views
Month 89: 21 views
Month 90: 26 views
Month 91: 22 views
Month 92: 33 views
Month 93: 35 views
Month 94: 21 views
Month 95: 28 views
Month 96: 31 views
Month 97: 19 views
Month 98: 28 views
Month 99: 22 views
Month 100: 23 views
Month 101: 12 views
Month 102: 17 views
Month 103: 20 views
Month 104: 14 views
Month 105: 35 views
Month 106: 18 views
Month 107: 34 views
Month 108: 41 views
Month 109: 33 views
Month 110: 33 views
Month 111: 34 views
Month 112: 29 views
Month 113: 18 views
Month 114: 39 views
Month 115: 19 views
Month 116: 26 views
Month 117: 19 views
Month 118: 22 views
Month 119: 40 views
Month 120: 35 views
Month 121: 14 views
Month 122: 20 views
Month 123: 25 views
Month 124: 22 views
Month 125: 33 views
Month 126: 22 views
Month 127: 38 views
Month 128: 33 views
Month 129: 35 views
Month 130: 49 views
Month 131: 25 views
Month 132: 28 views
Month 133: 44 views
Month 134: 59 views
Month 135: 66 views
Month 136: 50 views
Month 137: 50 views
Month 138: 69 views
Month 139: 35 views
Month 140: 55 views
Month 141: 48 views
Month 142: 41 views
Month 143: 40 views

Total Views: 869

Total Downloads: 66

All Trends