Preparation of Capsules containing L-Cysteine with Melting Dispersion Cooling Method

1
Masato Tanaka
Masato Tanaka
2
Satoko Mesaki
Satoko Mesaki
3
Yoshinari Taguchi
Yoshinari Taguchi
1 Niigata University

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GJMR Volume 14 Issue C6

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It was tried to prepare the capsules containing L-cysteine with the melting dispersion cooling method. Tripalmitin was selected as the shell material in order to keep out water and a few fatty acid esters such as ethyl laurate, ethyl stearate, ethyl myristate, ethyl oleate, ethyl palmitate and bees wax were added in the shell material as the modification materials in order to improve the water proof of the capsule shell. Furthermore, the capsules were coated by the coating materials such as oleic acid, ethyl oleate, triolein and ethyl laurate. It was investigated how the concentration of oil soluble surfactant and the combination of the shell material with both the modification materials and the coating materials affected the characteristics of capsules such as the content and the release feature of core material, the water proof and the swelling degree of capsules. With increasing the concentration of oil soluble surfactant, the released ratio decreased, become minimum and then, increased. The content could be increased by addition of modification materials.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

Masato Tanaka. 2014. \u201cPreparation of Capsules containing L-Cysteine with Melting Dispersion Cooling Method\u201d. Global Journal of Medical Research - C: Microbiology & Pathology GJMR-C Volume 14 (GJMR Volume 14 Issue C6): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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v1.2

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November 5, 2014

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English

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It was tried to prepare the capsules containing L-cysteine with the melting dispersion cooling method. Tripalmitin was selected as the shell material in order to keep out water and a few fatty acid esters such as ethyl laurate, ethyl stearate, ethyl myristate, ethyl oleate, ethyl palmitate and bees wax were added in the shell material as the modification materials in order to improve the water proof of the capsule shell. Furthermore, the capsules were coated by the coating materials such as oleic acid, ethyl oleate, triolein and ethyl laurate. It was investigated how the concentration of oil soluble surfactant and the combination of the shell material with both the modification materials and the coating materials affected the characteristics of capsules such as the content and the release feature of core material, the water proof and the swelling degree of capsules. With increasing the concentration of oil soluble surfactant, the released ratio decreased, become minimum and then, increased. The content could be increased by addition of modification materials.

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Preparation of Capsules containing L-Cysteine with Melting Dispersion Cooling Method

Satoko Mesaki
Satoko Mesaki
Yoshinari Taguchi
Yoshinari Taguchi
Masato Tanaka
Masato Tanaka Niigata University

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