Quantitative Determination of Ethyl Methyl Hydroxypyridina Succinate in the Preparation Seroxidol and its Bioequivalence
Nowadays, the most common spread diseases are cerebral circulation disorders, including ischaemic stroke and its consequences, such as dyscirculatory encephalopathy, vegetative-vascular dystonia, neurotic and neurosis-like disorders, memory and attention disorders or mental impairment, and atherosclerosis of the cerebral vessels. Research on the need for new drugs for those neurological disorders in Uzbekistan has been done and successfully produced an injectable solution of Seroxidol. This drug is an inhibitor of free radical processes and a membrane protector with antihypoxic, stress-protective, nootropic, anticonvulsant and anxiolytic effects. Seroxidol increases the resistance to the effects of various damaging factors (shock, hypoxia and ischaemia, cerebral circulation disorders, alcohol intoxication and antipsychotic drugs with neuroleptics) and improves the functional state of the ischaemic myocardium. It effectively restores myocardial contractility in cases of reversible cardiac dysfunction. Seroxidol contains ethyl methyl hydroxypyridine succinate and sodium metabisulfite.
