Relationship between Premature Rupture of Membranes and Collagen Amount in Chorioamnionic Membranes in Term Pregnancy

Murat Bakacak; Mehmet SÃ¼hhabostancÄ±; Emine GÃ¼ven; Rukset Attar; Ã–zge KÄ±zÄ±lkale; Gazi YÄ±ldÄ±rÄ±m; Hasan EroÄŸlu

Relationship between Premature Rupture of Membranes and Collagen Amount in Chorioamnionic Membranes in Term Pregnancy

Hasan Eroğlu * §

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Murat Bakacak

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Mehmet SÃ¼hhabostancÄ±

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Emine Seda GÃ¼vendaÄŸ GÃ¼ven

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Rukset Attar

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Ã–zge KÄ±zÄ±lkale

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Gazi YÄ±ldÄ±rÄ±m

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§ Department of Obstetrics and Gynecology

Relationship between Premature Rupture of Membranes and Collagen Amount in Chorioamnionic Membranes in Term Pregnancy

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Abstract

Aim: Aim of this study is investigate the collagen amounts that have been deposited within the chorioamnionic membranes of term pregnancies by means of electron microscopy. Material and Methods: The study group was made up by 20 women with term pregnancies who were diagnosed with premature rupture of membranes (PROM). Control group consisted of 20 women with term pregnancies who had no leakage of amniotic fluid. Electron microscopy was utilized to assess the collagen amount within the tissue samples which were acquired from the chorioamnionic membranes of the patients. Results: When the control group was compared with the study group, term pregnancies with PROM were found to have statistically lower quantity of collagen within unit area of chorioamnionic membranes(Mean values are respectively 69.5% ± 26.3% vs 49.60% ± 23.44%; p=0.017; 95% confidence interval: 0.14-0.19) Conclusion: Many factors have been implicated in the etiology of PROM. The present study concludes that the decrease in collagen quantity is statistically significant in chorioamnionic membranes of term pregnant women with PROM.

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18 Cites in Article

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Hasan EroÄŸlu, Murat Bakacak, Mehmet SÃ¼hhabostancÄ±, Emine Seda GÃ¼vendaÄŸ GÃ¼ven, Rukset Attar, Ã–zge KÄ±zÄ±lkale, Gazi YÄ±ldÄ±rÄ±m. 2014. "Relationship between Premature Rupture of Membranes and Collagen Amount in Chorioamnionic Membranes in Term Pregnancy". Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 14 (GJMR Volume 14 Issue 19 (E2)).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

electron microscopy pregnancy premature rupture of membranes

Classification

GJMR-E Classification NLMC Code: WJ 190

Submission ReceivedDecember 8, 2013
Peer Review Double Blind
Handling Editor
Accepted January 1, 2014
Published April 28, 2014

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v1.2

Issue date

April 28, 2014

Language

English

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Article Matrices

Total Score: 114

Country: Turkey

Subject: Global Journal of Medical Research - E: Gynecology & Obstetrics

Authors: Hasan Eroğlu, Murat Bakacak, Mehmet Sühhabostancı, Emine Seda Güvendağ Güven, Rukset Attar, Özge Kızılkale, Gazi Yıldırım, Agahan Han, Dr. Ömer Kandemir (PhD/Dr. count: 1)

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