Rickettsial Infections: A Clinician’s Diagnostic Dilemma

Rickettsial Infections: A Clinician’s Diagnostic Dilemma

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Background

Abstract

Rickettsial diseases are arthropod borne zoonotic infections that are being increasingly recognized as one of the causes of pyrexia of unknown origin (PUO). These pathogens are gram-negative bacteria causing fever and rash, usually transmitted to humans by tick or flea bite. These infections must be differentiated from other febrile illnesses such as enteric fever, malaria, dengue, leptospirosis, and infectious mononucleosis. The common clinical presentation includes fever with chills and rigor, headache, vomiting, cough, conjunctival congestion and eschar. Presenting with varied and non-specific symptoms, ignorance, and low index of suspicion, they are often under-diagnosed due to the unavailability of the reliable diagnostic test. Weil-Felix test (WFT) is a non-specific heterophile tube agglutination test in which antibodies against rickettsiae are detected. If timely treatment with doxycycline is instituted the adverse consequences can be well averted.

References

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Sriranjani Iyer, Dr. Harsh Rajeev Mehta, Dr. Sarojini P. Jadhav. 2020. "Rickettsial Infections: A Clinician’s Diagnostic Dilemma". Global Journal of Medical Research - I: Surgeries & Cardiovascular System GJMR-I Volume 20 (GJMR Volume 20 Issue I1).

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  • Open Access
  • CC-BY-ND-NC 4.0
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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
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Classification
GJMR-I Classification DDC Code: 595.2041 LCC Code: QL434.72
  • Submission ReceivedDecember 13, 2019
  • Peer Review Double Blind
    Handling Editor
  • Accepted January 4, 2020
  • Published January 15, 2020
Version of record

v1.2

Issue date
May 21, 2020

Language
English
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Rickettsial Infections: A Clinician’s Diagnostic Dilemma

Dr. Iyer
Dr. Iyer
Dr. Mehta
Dr. Mehta
Dr. Jadhav
Dr. Jadhav
  • Submission ReceivedDecember 13, 2019
  • Peer Review Double Blind
    Handling Editor
  • Accepted January 4, 2020
  • Published January 15, 2020