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In this article we review the types of natural and synthetic materials that are being used in brain tissue engineering applications for traumatic brain injury and stroke. We analyse modifications of scaffolds including immobilizing drugs, growth factors and extracellular matrix molecules to improve central nervous system regeneration and functional recovery. This review attempts to outline the varieties of biomaterial parameters that are applied as biophysical and biochemical signals to direct NSC fate and behaviour. The understanding on the interaction of NSCs decision and biomaterial parameters is helping to advance NSCs-based clinical approaches for nerve tissue regeneration and repair.
Athira K.S.. 2015. \u201cRole of Biomaterials in Neural Stem Cell Fate\u201d. Global Journal of Science Frontier Research - G: Bio-Tech & Genetics GJSFR-G Volume 15 (GJSFR Volume 15 Issue G1): .
Crossref Journal DOI 10.17406/GJSFR
Print ISSN 0975-5896
e-ISSN 2249-4626
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Total Score: 102
Country: India
Subject: Global Journal of Science Frontier Research - G: Bio-Tech & Genetics
Authors: Athira K.S., Paulose C.S (PhD/Dr. count: 0)
View Count (all-time): 169
Total Views (Real + Logic): 4011
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Publish Date: 2015 10, Sat
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In this article we review the types of natural and synthetic materials that are being used in brain tissue engineering applications for traumatic brain injury and stroke. We analyse modifications of scaffolds including immobilizing drugs, growth factors and extracellular matrix molecules to improve central nervous system regeneration and functional recovery. This review attempts to outline the varieties of biomaterial parameters that are applied as biophysical and biochemical signals to direct NSC fate and behaviour. The understanding on the interaction of NSCs decision and biomaterial parameters is helping to advance NSCs-based clinical approaches for nerve tissue regeneration and repair.
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