Role of Biomaterials in Neural Stem Cell Fate

α
Athira K.S.
Athira K.S.
σ
Paulose C.S
Paulose C.S
α Indian Institute of Science Bangalore Indian Institute of Science Bangalore

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Role of Biomaterials in Neural Stem Cell Fate

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Abstract

In this article we review the types of natural and synthetic materials that are being used in brain tissue engineering applications for traumatic brain injury and stroke. We analyse modifications of scaffolds including immobilizing drugs, growth factors and extracellular matrix molecules to improve central nervous system regeneration and functional recovery. This review attempts to outline the varieties of biomaterial parameters that are applied as biophysical and biochemical signals to direct NSC fate and behaviour. The understanding on the interaction of NSCs decision and biomaterial parameters is helping to advance NSCs-based clinical approaches for nerve tissue regeneration and repair.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Athira K.S.. 2015. \u201cRole of Biomaterials in Neural Stem Cell Fate\u201d. Global Journal of Science Frontier Research - G: Bio-Tech & Genetics GJSFR-G Volume 15 (GJSFR Volume 15 Issue G1): .

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Issue Cover
GJSFR Volume 15 Issue G1
Pg. 35- 57
Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords
Classification
GJSFR-G Classification: FOR Code: 090301
Version of record

v1.2

Issue date

October 17, 2015

Language
en
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In this article we review the types of natural and synthetic materials that are being used in brain tissue engineering applications for traumatic brain injury and stroke. We analyse modifications of scaffolds including immobilizing drugs, growth factors and extracellular matrix molecules to improve central nervous system regeneration and functional recovery. This review attempts to outline the varieties of biomaterial parameters that are applied as biophysical and biochemical signals to direct NSC fate and behaviour. The understanding on the interaction of NSCs decision and biomaterial parameters is helping to advance NSCs-based clinical approaches for nerve tissue regeneration and repair.

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Role of Biomaterials in Neural Stem Cell Fate

Athira K.S.
Athira K.S. Indian Institute of Science Bangalore
Paulose C.S
Paulose C.S

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