Role of Cytosorb in Severe Covid 19 Patients to Combat Cytokine Storm – A Case Series of 3 Patients

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Dr. Nithish Sattoju
Dr. Nithish Sattoju
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Dr. Sai Sashank Merugu
Dr. Sai Sashank Merugu
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Dr. Santosh Gattu
Dr. Santosh Gattu
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Sai Ram Ganapaka
Sai Ram Ganapaka
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Vydhika Anneboina
Vydhika Anneboina

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Role of Cytosorb in Severe Covid 19 Patients to Combat Cytokine Storm – A Case Series of 3 Patients

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Abstract

Purpose: To demonstrate the effect of Cytosorb on reducing the cytokine levels seen due to cytokine storm in severe COVID 19 patients. Material & Methods: COVID 19 patients with severe HRCT scoring and on NIV/ MV were included in the study. The time points considered in our study are D0, D+1, D+3 & D+5, to look for the levels of inflammatory markers post therapy along with the outcome of patients on D+7 in terms of mortality or off NIV/ MV. Results: Statistical significance tested for the reduction in the WHO score value resulted p value of 0.85. The mean baseline value of the inflammatory markers, CRP, D-DIMER & IL 6 were 66.94, 780.67 &144.67 respectively with range 56.5-81, 331-1211 & 124-167 respectively & p values 0.60, 0.95 & 0.18 respectively. 7-day outcome of the study was 100% mortality.

References

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Nithish Sattoju. 2026. \u201cRole of Cytosorb in Severe Covid 19 Patients to Combat Cytokine Storm – A Case Series of 3 Patients\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 22 (GJMR Volume 22 Issue F5): .

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Alt text: Study on cytokors' role in Covid-19 patients and cytokine storm reduction.
Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification: DDC Code: 616.079 LCC Code: RM282.C95
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v1.2

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July 9, 2022

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en
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Purpose: To demonstrate the effect of Cytosorb on reducing the cytokine levels seen due to cytokine storm in severe COVID 19 patients. Material & Methods: COVID 19 patients with severe HRCT scoring and on NIV/ MV were included in the study. The time points considered in our study are D0, D+1, D+3 & D+5, to look for the levels of inflammatory markers post therapy along with the outcome of patients on D+7 in terms of mortality or off NIV/ MV. Results: Statistical significance tested for the reduction in the WHO score value resulted p value of 0.85. The mean baseline value of the inflammatory markers, CRP, D-DIMER & IL 6 were 66.94, 780.67 &144.67 respectively with range 56.5-81, 331-1211 & 124-167 respectively & p values 0.60, 0.95 & 0.18 respectively. 7-day outcome of the study was 100% mortality.

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Role of Cytosorb in Severe Covid 19 Patients to Combat Cytokine Storm – A Case Series of 3 Patients

Dr. Nithish Sattoju
Dr. Nithish Sattoju
Dr. Sai Sashank Merugu
Dr. Sai Sashank Merugu
Dr. Santosh Gattu
Dr. Santosh Gattu
Sai Ram Ganapaka
Sai Ram Ganapaka
Vydhika Anneboina
Vydhika Anneboina

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