Serum Homocysteine and Paraoxonase1 Levels in Women with Polycystic Ovary Syndrome Treated with Metformin Versus Metformin and Folic Acid

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Serum Homocysteine and Paraoxonase1 Levels in Women with Polycystic Ovary Syndrome Treated with Metformin Versus Metformin and Folic Acid

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References

28 Cites in Article
  1. 1. L Nardo,S Patchava,I Laing (2008). Polycystic ovary syndrome: Pathophysiology, molecular aspects and clinical implications. Panminerva Med, 50(4), 267-278.
  2. 2. J Oates,S Abraham (2010). LIEWELLYN-JONES Fundamentals of obstetrics and gynaecology 9 th edition. LIEWELLYN-JONES Fundamentals of obstetrics and gynaecology 9 th edition, 223-224.
  3. 3. B Presannakumari,Sareena Gilvaz (2011). Polycystic Ovarian Syndrome. Postgraduate Gynecology, 140-140.
  4. 4. E Keith (2011). Dewhurst ' s Textbook of Obstetrics and Gynaecology. Dewhurst ' s Textbook of Obstetrics and Gynaecology, 517
  5. 5. C De La,R Usandizga,M Sancha,F Magdaleon,A Herranz,E Carillo (2003). Homocysteine, Folic acid and B-group vitamins in obstetrics and gynecology. Eur. J. Obstet. Gynecol. Reprod. Biol, 107, 125-134.
  6. 6. Kirsten Holven,Pål Aukrust,Kjetil Retterstøl,Kari Otterdal,Vigdis Bjerkeli,Leiv Ose,Marit Nenseter,Bente Halvorsen (2008). The Antiatherogenic Function of HDL Is Impaired in Hyperhomocysteinemic Subjects. The Journal of Nutrition, 138(11), 2070-2075.
  7. 7. D Draganov,J Teiber,A Speelman,Y Osawa,R Sunahara,La Du,B (2005). Human paraoxonases (PON1, PON2 and PON3) are lactonases with overlapping and distinct substrate specificities. Journal of Lipid Research, 46, 1239-1247.
  8. 8. Joseph Loscalzo (2008). Paraoxonase and Coronary Heart Disease Risk. Circulation: Cardiovascular Genetics, 1(2), 79-80.
  9. 9. J Zhang,P Fan,H Liu,H Bai1,Wang,F Zhang (2012). Apolipoprotein A-I and B levels, dyslipidemia and metabolic syndrome in south-west Chinese women with PCOS. Hum Reprod, 27(8), 2484-2493.
  10. 10. Y Lee,S Choi,K Lee,D Kim (2011). Apolipoprotein B/A1 ratio is associated with free androgen index and visceral adiposity and may be an indicator of metabolic syndrome in male children and adolescents. Clin. Endocrinol (Oxf), 74, 579-586.
  11. 11. T Hiroyuki,K Shintaro,S Matsushima (2011). Oxidative stress and heart failure. Oxidative stress and heart failure, 8630-8638.
  12. 12. R Webster,V Roberts,L Myatt (2008). Protein nitration in placenta -functional signifycance. Placenta, 29, 985-994.
  13. 13. Kaïs Al-Gubory,Paul Fowler,Catherine Garrel (2010). The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes. The International Journal of Biochemistry & Cell Biology, 42(10), 1634-1650.
  14. 14. Dean Eurich,Finlay Mcalister,David Blackburn,Sumit Majumdar,Ross Tsuyuki,Janice Varney,Jeffrey Johnson (2007). Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review. BMJ, 335(7618), 497.
  15. 15. H Lashen (2010). Role of Metformin in the management of polycystic ovary syndrome. Ther. Adv. Endocrinol Metab, 1(3), 117-128.
  16. 16. L Xu,Z Huang,X Xiaoying He,X Wan,D Fang,Y Li (2013). Adverse effect of Metformin therapy on serum vitamin B12 andfolate: Short-term treatment causes disadvantages. Medical Hypotheses, 81(2), 149-151.
  17. 17. Signe Altmäe,Anneli Stavreus-Evers,Jonatan Ruiz,Margit Laanpere,Tiina Syvänen,Agneta Yngve,Andres Salumets,Torbjörn Nilsson (2010). Variations in folate pathway genes are associated with unexplained female infertility. Fertility and Sterility, 94(1), 130-137.
  18. 18. Y Goh,G Koren (2008). Folic acid in pregnancy and fetal outcomes. Journal of Obstetrics and Gynaecology, 28(1), 3-13.
  19. 19. M Schatchter,A Raziel,S Friedler,D Strassburger,O Orna Bern,R Ron-El (2003). Insulin resistance in patients with polycystic ovary syndrome is associated with elevated plasma homocysteine. Human Reproduction, 18(4), 721-727.
  20. 20. Esra Kilicdag,Tayfun Bagis,Ebru Tarim,Erdogan Aslan,Serkan Erkanli,Erhan Simsek,Bulent Haydardedeoglu,Esra Kuscu (2005). Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin: a randomized trial. Human Reproduction, 20(6), 1521-1528.
  21. 21. Stefano Palomba,Angela Falbo,Francesco Giallauria,Tiziana Russo,Achille Tolino,Fulvio Zullo,Annamaria Colao,Francesco Orio (2010). Effects of Metformin With or Without Supplementation With Folate on Homocysteine Levels and Vascular Endothelium of Women With Polycystic Ovary Syndrome. Diabetes Care, 33(2), 246-251.
  22. 22. E Kilicdag,T Bagis,E Tarim,E Aslan,S Erkanli,E Simsek,B Haydardedeoglu,E Kuscu (2005). Homocysteine levels in polycystic ovarian syndrome treated with Metformin versus rosiglitazone. Human Reproduction, 20(4), 894-899.
  23. 23. Murat Yilmaz,Neslihan Bukan,Göksun Ayvaz,Ayhan Karakoç,Füsun Törüner,Nuri Çakir,Metin Arslan (2005). The effects of rosiglitazone and metformin on oxidative stress and homocysteine levels in lean patients with polycystic ovary syndrome. Human Reproduction, 20(12), 3333-3340.
  24. 24. Necat Yilmaz (2012). State of the art paper Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases. Archives of Medical Science, 1(1), 138-153.
  25. 25. Clifford Bailey (2008). Metformin: Effects on Micro and Macrovascular Complications in Type 2 Diabetes. Cardiovascular Drugs and Therapy, 22(3), 215-224.
  26. 26. E Nakano,J Higgins,H Powers (2001). Folate protects against oxidative modification of human LDL. Br. J. Nutr, 86, 637-639.
  27. 27. E Elia,V Sander,C Luchetti,M Solano,G Girolamo,Di,C Gonzalez,A Motta1 (2006). The mechanisms involved in the action of Metformin in regulating ovarian function in hyperandrogenized mice. Molecular Human Reproduction, 12(8), 475-481.
  28. 28. J Racek,Rusnakova,L Trefil,K Siala (2005). The influence of folate and antioxidants on homocysteine levels and oxidative stress in patients with hyperlipidemia and hyperhomocysteinemia. Physiol. Res, 54, 87-95.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Qusay Mohsin Kadium. 2013. "Serum Homocysteine and Paraoxonase1 Levels in Women with Polycystic Ovary Syndrome Treated with Metformin Versus Metformin and Folic Acid". Global Journal of Science Frontier Research - G: Bio-Tech & Genetics GJSFR-G Volume 13 (GJSFR Volume 13 Issue G2).

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords
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GJSFR-G Classification FOR Code: 320307p
100499
Version of record

v1.2

Issue date
October 30, 2013

Language
English
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Serum Homocysteine and Paraoxonase1 Levels in Women with Polycystic Ovary Syndrome Treated with Metformin Versus Metformin and Folic Acid

Qusay Kadium
Qusay Kadium University of Babylon