Simple UV Spectrophotometric Assay of Atorvastatin API Formulation and their Comparative Study

Simple UV Spectrophotometric Assay of Atorvastatin API Formulation and their Comparative Study

Dr. Safila Naveed

Contact

α Jinnah University for Women

Simple UV Spectrophotometric Assay of Atorvastatin API Formulation and their Comparative Study

Article Fingerprint

ReserarchID

PDDTMH74D8

Simple UV Spectrophotometric Assay of Atorvastatin API Formulation and their Comparative Study Banner

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

A rapid, simple, accurate, and economical least time consuming rosuvastatin spectrophotometric method has been developed for the assay of atorvastatin and then compare assay of brand available in Karachi,Pakistan. The assay is based on the ultraviolet UV absorbance maxima at about 244nm wavelength of atorvastatin using methanol as solvent. A sample of drug was dissolved in methanol to produce a solution containing atorvastatin. Similarly, a sample of ground tablets of different brand were extracted with methanol and diluted with the same methanol. The absorbance of sample preparation was measured at 244 nm against the solvent blank and the assay was determined by comparing with the absorbance of available brand. The method can be applied for the routine QC quantitation of atorvastatin in tablet formulation and active.

References

10 Cites in Article

Reference Format

Jonathan Tobert (2003). Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
P Jones,M Davidson,E Stein,H Bays,J Mckenney,E Miller (2003). Unknown Title.
M Caslake,G Stewart,S Day,E Daly (2003). Unknown Title.
J Mckenney,Am (2005). Unknown Title.
Kwang Koh,Michael Quon,Seung Han,Wook-Jin Chung,Jeong Ahn,Yiel-Hea Seo,Moon Kang,Tae Ahn,In Choi,Eak Shin (2004). Additive Beneficial Effects of Losartan Combined With Simvastatin in the Treatment of Hypercholesterolemic, Hypertensive Patients.
Najma Sultana,M Arayne,Safila Naveed (2010). Simultaneous Determination of Captopril and Statins in API, Pharmaceutical Formulations and in Human Serum by RP‐HPLC.
Najma Sultana,M Arayne,Shabana Shah,Nighat Shafi,Safila Naveed (2010). Simultaneous Determination of Prazosin, Atorvastatin, Rosuvastatin and Simvastatin in API, Dosage Formulations and Human Serum by RP‐HPLC.
N Sultana,M Arayne,Safila Naveed (2011). Validated Method for the Simultaneous Determination of Lisinopril, Pravastatin, Atorvastatin and Rosuvastatin in API, Formulations and Human Serum by RP-HPLC.
Najma Sultana,M Arayne,Safila Naveed (2011). SIMULTANEOUS DETERMINATION OF ENALAPRIL AND STATIN'S IN PHARMACEUTICAL FORMULATIONS BY RP-HPLC.
M Arayne,N Sultana,Arman,Tabassum Saeeda,Nadir Ali,Safila Naveed (2012). Simultaneous LC Determination of Rosuvastatin, Lisinopril, Captopril, and Enalapril in API, Pharmaceutical Dosage Formulations, and Human Serum Medicinal.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Safila Naveed. 2014. \u201cSimple UV Spectrophotometric Assay of Atorvastatin API Formulation and their Comparative Study\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 14 (GJMR Volume 14 Issue B2): .

More Citation Formats

Select Citation Style:

Download Citation

Download Article

GJMR Volume 14 Issue B2
Pg. 35- 38

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

assay atorvastatin uv pectrophotometry

Submission ReceivedDecember 6, 2013
Peer Review Double Blind
Handling Editor
Accepted January 5, 2014
Published January 15, 2014

Version of record

v1.2

Issue date

June 3, 2014

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Score: 106

Country: Pakistan

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Dr. Safila Naveed (PhD/Dr. count: 1)

View Count (all-time): 149

Total Views (Real + Logic): 4670

Total Downloads (simulated): 2350

Publish Date: 2014 06, Tue

Monthly Totals (Real + Logic):

Month 1: 64 views
Month 2: 59 views
Month 3: 53 views
Month 4: 37 views
Month 5: 26 views
Month 6: 48 views
Month 7: 28 views
Month 8: 31 views
Month 9: 35 views
Month 10: 52 views
Month 11: 37 views
Month 12: 30 views
Month 13: 29 views
Month 14: 48 views
Month 15: 36 views
Month 16: 35 views
Month 17: 22 views
Month 18: 16 views
Month 19: 18 views
Month 20: 44 views
Month 21: 22 views
Month 22: 36 views
Month 23: 31 views
Month 24: 18 views
Month 25: 37 views
Month 26: 20 views
Month 27: 35 views
Month 28: 33 views
Month 29: 22 views
Month 30: 16 views
Month 31: 31 views
Month 32: 24 views
Month 33: 24 views
Month 34: 29 views
Month 35: 22 views
Month 36: 22 views
Month 37: 32 views
Month 38: 42 views
Month 39: 29 views
Month 40: 29 views
Month 41: 23 views
Month 42: 36 views
Month 43: 27 views
Month 44: 24 views
Month 45: 42 views
Month 46: 31 views
Month 47: 38 views
Month 48: 39 views
Month 49: 49 views
Month 50: 28 views
Month 51: 32 views
Month 52: 23 views
Month 53: 38 views
Month 54: 29 views
Month 55: 30 views
Month 56: 32 views
Month 57: 33 views
Month 58: 40 views
Month 59: 25 views
Month 60: 41 views
Month 61: 14 views
Month 62: 13 views
Month 63: 24 views
Month 64: 27 views
Month 65: 16 views
Month 66: 48 views
Month 67: 43 views
Month 68: 22 views
Month 69: 40 views
Month 70: 32 views
Month 71: 23 views
Month 72: 26 views
Month 73: 21 views
Month 74: 36 views
Month 75: 43 views
Month 76: 35 views
Month 77: 36 views
Month 78: 35 views
Month 79: 36 views
Month 80: 25 views
Month 81: 43 views
Month 82: 27 views
Month 83: 18 views
Month 84: 31 views
Month 85: 26 views
Month 86: 23 views
Month 87: 30 views
Month 88: 33 views
Month 89: 48 views
Month 90: 38 views
Month 91: 32 views
Month 92: 38 views
Month 93: 37 views
Month 94: 26 views
Month 95: 38 views
Month 96: 39 views
Month 97: 20 views
Month 98: 30 views
Month 99: 45 views
Month 100: 45 views
Month 101: 45 views
Month 102: 37 views
Month 103: 15 views
Month 104: 18 views
Month 105: 40 views
Month 106: 25 views
Month 107: 45 views
Month 108: 42 views
Month 109: 39 views
Month 110: 40 views
Month 111: 34 views
Month 112: 23 views
Month 113: 26 views
Month 114: 30 views
Month 115: 41 views
Month 116: 27 views
Month 117: 28 views
Month 118: 46 views
Month 119: 14 views
Month 120: 31 views
Month 121: 19 views
Month 122: 41 views
Month 123: 25 views
Month 124: 21 views
Month 125: 18 views
Month 126: 27 views
Month 127: 29 views
Month 128: 42 views
Month 129: 32 views
Month 130: 39 views
Month 131: 28 views
Month 132: 19 views
Month 133: 11 views
Month 134: 24 views
Month 135: 18 views
Month 136: 32 views
Month 137: 31 views
Month 138: 19 views
Month 139: 37 views
Month 140: 41 views
Month 141: 47 views
Month 142: 45 views
Month 143: 54 views

Total Views: 4670

Total Downloads: 2350

2026 Trends

Published Article

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]