Sntheses and Applications of Pyrimidinethiones

1
Mohamed Abdel-Megid
Mohamed Abdel-Megid
2
K.M. Elmahdy
K.M. Elmahdy
3
Aymn E. Rashad
Aymn E. Rashad
1 Ain-Shams University

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One important class of pyrimidine is pyrimidinethione, which is also well known as mercapto or thioxopyrimidine compounds. This review deals with the synthesis and applicaions of pyrimidinethiones.

163 Cites in Articles

References

  1. Sham Sondhi,Rajendra Goyal,Anand Lahoti,Nirupma Singh,Rakesh Shukla,Ram Raghubir (2005). Synthesis and biological evaluation of 2-thiopyrimidine derivatives.
  2. Artem Khvorostov,Leszek Lapinski,Hanna Rostkowska,Maciej Nowak (2006). Unimolecular proton-transfer photoreactions in 2,4-dithiouracil and 6-aza-2,4-dithiouracil: A matrix isolation study.
  3. M Wojcik,M Boczar,M Wieczorek,W Tatara (2000). Unknown Title.
  4. A Sammour,M Selim,Nour El-Deen,M,Abd El-Halim,M,U (1970). Unknown Title.
  5. M El-Hashash,A El-Kafrawy,S Shiba (1991). Unknown Title.
  6. T Takeshima,Imamato,M Tokoyama,K Yamamoto,M Akano (1968). Unknown Title.
  7. Z Khalaf,A Yanni,A Abdel-Hafez,A Khalaf (1990). Unknown Title.
  8. (1991). Notice.
  9. M Badr,M Barsy,M Selim,Abd El-Latif,F (1992). Unknown Title.
  10. David Cope (1993). The Vigil.
  11. M El-Hashash,, Mahmoud,S Mdboli (1993). Unknown Title.
  12. David Cope (1993). The Vigil.
  13. F Soliman,M El-Hashash,L Sauka,A Salem (1996). Unknown Title.
  14. (1996). Unknown Title.
  15. A Wasfy,,M Amine,,A Eissa, (1996). SYNTHESIS AND REACTIONS OF 6(4)-(P-BENZYLPHENYL)-4(6)-PHENYLPYRIMIDINE-2( 1H) THIONE.
  16. (1997). Author Index for Volume 126.
  17. K Yossef,M Badran (1992). Egypt.
  18. (1992). Unknown Title.
  19. G Ahmed (1995). Unknown Title.
  20. M Yousef,H Eisa,M Nasr,S El-Bialy (1996). Unknown Title.
  21. (1996). Author index volume 125 (1996).
  22. O El-Sayed,M El-Semary,M Khalil (1996). Unknown Title.
  23. (1996). Author index volume 125 (1996).
  24. T Abdel Rahman (1998). Income Disparity, Time Allocation, and Social Welfare in a System of Cities.
  25. (2000). Unknown Title.
  26. V M Barot,S Modi,H Naik (2000). Unknown Title.
  27. (2000). Dialog.
  28. A El-Kafrawy,F El-Bassiouny,M Sayed,M El-Hashash (1992). Unknown Title.
  29. M Ali,M El-Kachef,A Hammam (1974). Unknown Title.
  30. M Ali,A Abd-Elfateh,H Hammoada (1976). Unknown Title.
  31. S Naik,R Behera,A Nayak (1982). Unknown Title.
  32. A Athia,M Micheal (1938). Unknown Title.
  33. Pranab Mahata,U Syam Kumar,V Sriram,H Ila,H Junjappa (2003). 1-Bis(methoxy)-4-bis(methylthio)-3-buten-2-one: useful three carbon synthon for synthesis of five and six membered heterocycles with masked (or unmasked) aldehyde functionality.
  34. R Verma (1999). Unknown Title.
  35. (2000). Unknown Title.
  36. C Brianc,G (1987). Unknown Title.
  37. G Rovnyak,S Kimball (1992). Unknown Title.
  38. Editors Gesnerus (1992). Preliminary materials.
  39. C Tice (1994). Unknown Title.
  40. (1995). Unknown Title.
  41. R Hant,J Meomie,E Sayer (1959). Unknown Title.
  42. B Tore,U Kjell (1982). Unknown Title.
  43. K Atwal,B O'reilly,J Gougoutas,M Malley,Heterocycles,S Sondhi,R Goyal,A Lahoti,N Singh,R Shukla,R Raghubir (1987). Unknown Title.
  44. D Brown,W Cowden,S Lan,K Mori (1984). Heterocyclic amplifiers of phleomycin. I. Some pyrimidinylpurines, pyrimidinylpteridines and phenylpyrimidines.
  45. M Brokke (1960). Unknown Title.
  46. (1960). Unknown Title.
  47. P Evana (1893). Unknown Title.
  48. W Halle,S William (1951). Unknown Title.
  49. Fawzy Attaby,Sanaa Eldin (1999). Synthesis of Pyrimidine, Thiazolopyrimidine, Pyrimidotriazine and Triazolopyrimidine Derivatives and their Biological Evaluation.
  50. H El-Subbagh (1990). Unknown Title.
  51. M El-Gaby,S Abdel-Hamide,M Ghorab,S El-Sayed (1999). Unknown Title.
  52. (2000). Dialog.
  53. Kamaljit Singh,Jasbir Singh,Prasant Deb,Harjit Singh (1999). An expedient protocol of the Biginelli dihydropyrimidine synthesis using carbonyl equivalents.
  54. (2000). Unknown Title.
  55. C Kashima,A Katoh (1980). Unknown Title.
  56. Christian Kappe,Peter Roschger (1989). Synthesis and reactions of “biginelli‐compounds”. Part I.
  57. P Utala,P Raghuwanshi,A Doshi (1999). Unknown Title.
  58. (2000). Dialog.
  59. H Hintermaier,U Maier,S Weiss (1994). Unknown Title.
  60. (1994). Unknown Title.
  61. H Koike,M Kabaki,M Watanabe,Jpn,Kokai (1993). Unknown Title.
  62. (1995). Unknown Title.
  63. R Dodson,E Peterson,J Seyler (1950). Unknown Title.
  64. C Kappe,Georg Uray,Peter Roschger,Wolfgang Lindner,Christoph Kratky,Walter Keller (1992). Synthesis and reactions of biginelli compounds −5. Facile preparation and resolution of a stable 5-dihydropyrimidinecarboxylic acid..
  65. P Isherwood (1909). Unknown Title.
  66. (1910). Unknown Title.
  67. A Singh,R Mohem,V Misra (1985). Unknown Title.
  68. (1986). Unknown Title.
  69. E Zigeler,E Steiner (1965). Unknown Title.
  70. (1965). Front Matter Volume 63 Issue 1 1965.
  71. J Soto (1985). Unknown Title.
  72. O Tarasova,S Amosova (1983). Unknown Title.
  73. V Gupta,F Huennekens (1967). Thyminyl Derivatives of Tetrahydrofolate<sup>*</sup>.
  74. S Ahmed (2002). Unknown Title.
  75. J Schmeyers,G Kaupp (2002). Unknown Title.
  76. A Hammam,M Ali (1981). Unknown Title.
  77. Achim Musiol (1981). Schlußfolgerung.
  78. M Abdel-Megid (1998). SYNTHESIS OF PYRIMIDO [4,5-d] PYRIMIDINETHIONE DERIVATIVES AS BIOCIDAL AGENTS.
  79. R Fikry (1995). Unknown Title.
  80. L Gacia,A Lorente,L Soto (1982). Unknown Title.
  81. Satoshi Kambe,Koji Saito,Hiroshi Kishi,Akio Sakurai,Hiroshi Midorikawa (1979). A One-Step Synthesis of 4-Oxo-2-thioxopyrimidine Derivatives by the Ternary Condensation of Ethyl Cyanoacetate, Aldehydes, and Thiourea.
  82. S Abdel-Aziz (1996). FUSED CYANOPYRIMIDINES: PART-I SYNTHESIS AND REACTIONS OF FUSED CYANOPYRIMIDINE DERIVATIVES AND THEIR EFFECT ON CELLOBIASE ACTIVITY.
  83. A Sammour,M Abdallah,H Zoorob (1976). Preparation and some Reactions of 4‐Phenyl‐6‐(2‐thienyl)‐2(1H)‐pyridone Derivatives.
  84. A Ismail,M Sayed,A Soliman,A Radwan,M Khalil (1990). Unknown Title.
  85. A Tantawy,M Tayel,L Gad,M El-Ashmawy (1989). Unknown Title.
  86. S Hussain,A El-Barbary,S Mansour (1985). Unknown Title.
  87. C Whilehead (1952). The Synthesis of 5-Carbethoxyuracils.
  88. Ctba Ltd (1963). Carr, Rupert Ellis, (16 Feb. 1910–14 May 1974), Chairman: The Associated Biscuit Manufacturers Ltd, 1963–69; Peek, Frean & Co. Ltd, 1963–68; Meltis Ltd, 1963–68.
  89. Peter Safar (1963). Summary.
  90. T Stanek (1958). Unknown Title.
  91. (1958). Publications.
  92. E Ballard,T Johnson (1942). Unknown Title.
  93. K Kosegi,T Ichikawa,M Sawada,Y Ishizuka,T Kamisaki,H Yaginuma,M Oki (1990). Manufacture of high-octane gasoline I. Suzuki; K. Hirabayashi; T. Kondo; H. Nishijima Technology Research Association for New Application Development for Light-Weight Fractions Jpn Kokai Tokkyo Koho 87,151,490, July 6, 1987; Appl. Dec. 26, 1985.
  94. (1991). 10.1016/s1553-3212(06)71640-5.
  95. Hamed Daboun,Ahmed El-Reedy (1983). A One Step Synthesis of New 4-Aminopyrimidine Derivatives: Preparation of Tetrazolo- and s-Triazolopyrimidines.
  96. K El-Shahat,K Hassan,N Esmail,M El-Nagdi (1984). Unknown Title.
  97. M Jachak,M Mittelbach,H Junek (1993). Unknown Title.
  98. Rafat Mohareb,Sherif Sherif,Hussein Zohdi (1993). Heterocyclic Synthesis with Enamines: Convenient Syntheses of Polyfunctionally Substituted Pyrazole, Pyridine, Pyrimidine and Pyrazolo[3,4‐<i>d</i>]pyrimrdine Derivatives.
  99. (1993). Unknown Title.
  100. A Shutalev,L Ignatova (1993). N-glycosides. 9. Reaction of 3,5-O-isopropylidenexylofuranosylamine with ?-isothiocyanatoaldehydes. Synthesis of new cyclonucleosides with a hexahydropyrimidine aglycone.
  101. Michel Polonovski,René‐guy Busnel,Marcel Pesson (1948). Propriétés biochimiques des ptérines.
  102. H Coenen,R Olsson (2006). Unknown Title.
  103. Q Zhang,L Lu (2000). Unknown Title.
  104. S Ibrahim (1996). Unknown Title.
  105. (1996). Author index volume 125 (1996).
  106. R Melik-Ogandznyan,R Mirzoyan,A Aroyan (1975). Unknown Title.
  107. (1975). Unknown Title.
  108. G Kollenz,O Kappe (1988). Unknown Title.
  109. R Plate (1994). Unknown Title.
  110. (1994). Comment.
  111. V Ram,N Haque,A Shoeb (1992). Chemotherapeutic Agents. XXIV. Synthesis of Pyrazolo [3,4-d] pyrimidines as Isostere of Purines.
  112. M Leach,M Nobbs (1991). Unknown Title.
  113. (1992). Unknown Title.
  114. A Jain,S Sondhi,Vinay Sharma (2000). Synthesis, Characterization and Hg(II) Ion Selectivity of 1-(2-Nitro-4-methyl phenyl)-6-methyl-6-methoxy-1,4,5,6-tetrahydro-pyrimidine-2-(3H) thione (TPT).
  115. (2000). Dialog.
  116. S Sondhi,B Gupta,R Sahu,R Verma,P (1996). Unknown Title.
  117. (1996). Author index volume 125 (1996).
  118. S Sen,V Srivastava (1989). Feature.
  119. B Feit,A Teuerstein (1973). Unknown Title.
  120. T Ganca,C Macias,C Velez (1992). Unknown Title.
  121. (1992). 8. Karyotyp.
  122. G Furin,I Bagryanskaya,Yu. Gatilov (1997). Reaction of perfluoro-2-methylpent-2-en-3-yl isothiocyanate with methylamine.
  123. (1998). Unknown Title.
  124. Rafat Mohareb,Sherif Sherif,Hussein Zohdi (1993). Heterocyclic Synthesis with Enamines: Convenient Syntheses of Polyfunctionally Substituted Pyrazole, Pyridine, Pyrimidine and Pyrazolo[3,4‐<i>d</i>]pyrimrdine Derivatives.
  125. M Mohamed,N Ibrahim,M El-Nagdi (1987). El Nagdi, Omar.
  126. M Assy,H Moustafa (1995). REACTION OF AROYL ISOTHIOCYANATE WITH ACTIVE METHYLENE COMPOUNDS.
  127. L Gerus,M Gorbunova,S Vdovenko,Y Yagupolski,V Kukhar (1991). Unknown Title.
  128. F Gordeev,A Komkov,A Dorokhov (1990). Unknown Title.
  129. (1991). Unknown Title.
  130. Antonio Lorente,M Luisa Garc誕,Misericordia Fern�dez,Jos� L. Soto (1992). Reaction of Ketene Dithioacetals with Thioamides. A Synthesis of Pyrimidine Derivatives.
  131. K Shinya,T Yoshinori,H Akira (1988). Unknown Title.
  132. K Sasse,Justs (1976). Unknown Title.
  133. J Sauer (1967). Diels‐Alder reactions II: The Reaction Mechanism.
  134. D Brown,T Teitei (1964). 609. Simple pyrimidines. Part VI. The dominant tautomer in aqueous 4-hydroxy-6-mercaptopyrimidine.
  135. B Brien,B Dobner,G Wagner (1992). Unknown Title.
  136. (1992). Erratum.
  137. Joachim Goerdeler,Hermann Pohland (1961). Über Isothiazole, I. Darstellung und Oxydation einiger β‐Amino‐thiocrotonamide.
  138. J Goerdeler,D Wieland (1967). Unknown Title.
  139. S El-Bahaie,A Kadry,M Assy,Y Ibrahim (1988). Unknown Title.
  140. S El‐bahaie,M Assy (1989). ChemInform Abstract: 2‐(2‐Arylvinyl)thieno(2,3‐d)pyrimidines..
  141. S Rajappa,R Sreenivasan (1971). Unknown Title.
  142. Joachim Goerdeler,Dieter Wieland (1967). Synthese von Pyrimidinthionen‐(4) und Pyrazolo[3.4‐<i>d</i>]pyrimidinen.
  143. Ahmed Elghandour,Mahmoud Ramiz,Mohamed Elnagdi (1989). Novel Synthesis of Polyfunctionally Substituted Pyridines and Pyrimidines.
  144. J Krech,Z Miguel,J Francisco,J Soto (1988). Unknown Title.
  145. Bir Sain,Satyendra Singh,Jagir Sandhu (1991). Diazabutadienes in heterocyclic syntheses: reaction of 1,3-diazabutadienes with 2-oxazolin-5-ones.
  146. A Lorente,L Garcia,G Lapez,L Soto (1985). Unknown Title.
  147. Ernst Kluwe (1985). Bildnispropaganda und römischer Kunsthandel.
  148. M Dzurilla,P Kutschy,D Koscik (1987). Unknown Title.
  149. (1988). Unknown Title.
  150. Detlef Briel,Joachim Sieler,Günther Wagner,Wolfgang Schade (1988). SYNTHESIS OF 6-IMINO-6H-1,3-THIAZINES.
  151. R Zakrzewski,W Ciesielski (2005). Detection of mercaptopyridines and mercaptopyrimidines in planar chromatography with iodine–azide reaction as a detection system.
  152. S El‐bahaie,M Assy (1989). ChemInform Abstract: 2‐(2‐Arylvinyl)thieno(2,3‐d)pyrimidines..
  153. (1990). Unknown Title.
  154. K Ghoneim,F El-Telbany,M El-Enany,K Youssef (1988). Egypt.
  155. (1989). Unknown Title.
  156. K Steinbeck,W Brandes,G Haenssler,P Reinecke (1983). Unknown Title.
  157. (1986). Unknown Title.
  158. J Minatelli,A Brewer (1983). Eloge: Derek John deSolla Price (22 January 1922-3 September 1983).
  159. K Minn,P Braun,B Sachse,H Wicke (1990). Unknown Title.
  160. N Agarwal,P Srivastava,S Raghuwanshi,D Upadhyay,S Sinha,P Shukla,V Ram (2002). Unknown Title.
  161. R Vig,C Mao,T Venkatachalam,L Tuel-Ahlgren,E Sudbeck,F Uckun (1998). Unknown Title.
  162. M Holschbach,D Bier,S Stüsgen,W Wutz,W Sihver,Y He,F Chen,G Sun,Y Wang,E De Clercq,J Balzarini,C Pannecouque (2004). Unknown Title.
  163. Abdel-Galil E. Amr,Ashraf Mohamed,Salwa Mohamed,Nagla Abdel-Hafez,Abu El-Fotooh G. Hammam (2006). Anticancer activities of some newly synthesized pyridine, pyrane, and pyrimidine derivatives.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

Mohamed Abdel-Megid. 2013. \u201cSntheses and Applications of Pyrimidinethiones\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 13 (GJSFR Volume 13 Issue B7): .

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Crossref Journal DOI 10.17406/GJSFR

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One important class of pyrimidine is pyrimidinethione, which is also well known as mercapto or thioxopyrimidine compounds. This review deals with the synthesis and applicaions of pyrimidinethiones.

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Sntheses and Applications of Pyrimidinethiones

Mohamed Abdel-Megid
Mohamed Abdel-Megid Ain-Shams University
K.M. Elmahdy
K.M. Elmahdy
Aymn E. Rashad
Aymn E. Rashad

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