Solitary plasmacytoma is a rare neoplasm characterized by localized proliferation of monoclonal plasma cells and excessive production of the paraprotein M immunoglobulin; it’s generally asymptomatic. When plasmacytomas present as isolated lesions, they are referred to as solitary plasmacytomas (SP). Solitary plasmacytoma is distinguished from multiple myeloma by the absence of the International Myeloma Working Group (IMWG)–defined criteria (criteria as > 10% of clonal plasma cells within bone marrow or biopsy-proven bony or EMP, and at least 1 myeloma-defining event).

We report an extremely rare case of a 59-year-old woman who presented to the emergency department of our hospital in Chivasso, in the province of Turin, for unrelated reasons. During flexible fiberoptic endoscopic evaluation, an incidental pedunculated mass arising from the inferior portion of the right torus tubarius was identified.