Solvent Polarity and Temperature Effects on Extracted Secondary Metabolite from the Fruit of Tetrapleura Tetraptera and its Antibacterial Potential on Uropathogens

Solvent Polarity and Temperature Effects on Extracted Secondary Metabolite from the Fruit of Tetrapleura Tetraptera and its Antibacterial Potential on Uropathogens

Ololade Zacchaeus S.

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Solvent Polarity and Temperature Effects on Extracted Secondary Metabolite from the Fruit of Tetrapleura Tetraptera and its Antibacterial Potential on Uropathogens

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Abstract

Odoriferous medicinal plants are known to be used as natural therapeutic agents, as they are rich sources of terpenoids and polyphenols. This study was aimed at evaluating the solvent polarity, temperature effects and synergistic potential of the phytochemicals in the fruit extract obtained from the fruit of Tetrapleura tetraptera on clinically isolated uropathogens. T. tetraptera has being used locally in treating some ailments. The sample was extracted using methanol, hot water and cold water respectively. The quantitative and qualitative compositional analysis of the secondary metabolites of the fruit extract was carried out using Gas chromatography-mass spectrometry (GC-MS). The antibacterial screening was carried out using agar-well diffusion assay. The GC-MS analysis of the fruit extract led to the identification of thirtyfive (35) constituents amounting to 96.28% of the extract.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Ololade Zacchaeus S.. 2026. \u201cSolvent Polarity and Temperature Effects on Extracted Secondary Metabolite from the Fruit of Tetrapleura Tetraptera and its Antibacterial Potential on Uropathogens\u201d. Global Journal of Medical Research - C: Microbiology & Pathology GJMR-C Volume 22 (GJMR Volume 22 Issue C1).

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GJMR Volume 22 Issue C1

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-C Classification DDC Code: 150.195 LCC Code: BF408

Submission ReceivedJanuary 8, 2022
Peer Review Double Blind
Handling Editor
Accepted January 29, 2022
Published February 12, 2022

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v1.2

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March 17, 2022

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