Spectrophotometric Determination of Sodium Salicylate in Pharmaceutical Preparations by Coupling with Diazotized Paraamino Benzoic Acid

Mohauman Mohammad Al-Rufaie

Spectrophotometric Determination of Sodium Salicylate in Pharmaceutical Preparations by Coupling with Diazotized Paraamino Benzoic Acid

Mohauman Mohammad Al-Rufaie * §

Contact

§ Kufa University

Spectrophotometric Determination of Sodium Salicylate in Pharmaceutical Preparations by Coupling with Diazotized Paraamino Benzoic Acid

Article Fingerprint

ReserarchID

D86OJ

Key Research Insights

Synthesized scholarly intelligence & interactive research assistant

This converted HTML version may contain rendering inconsistencies. Please refer to the PDF for the authoritative version, or click here to provide feedback.

Abstract

A rapid, sensitive and simple spectrophotometric procedure for the assay of the smaller amounts measures from sodium salicylate at pharmaceutical preparations (topical-solution) was examined. The procedure is focus on a diazotization and reaction coupling between sodium salicylate and diazotized para-amino benzoic acid in alkaline medium for the formation of an intensive bright yellow soluble water colour which was being stable, which gives highly absorption at 452nm. The law of Beer was Introduced on the range of concentration from(2-30) μg.ml -1 of sodium salicylate, the molar absorptivity and the sensitivity of Sandell index were 8.5013×10 3 l mol -1 cm -1 , 0.0188 μg/cm 2 subsequently, The procedure does not need to the control of temperature and the extraction by the solvent. The perfect circumstances for all colour increasing are portrayed and the examined procedure has been very good application on the assay of sodium salicylate at topical-solution preparations. The general excipients materials and additives did not affect the examined procedure.

References

16 Cites in Article

Reference Format

1. Krishna Prasad (2007). Regulatory Issues Affecting Cardiologists in Europe. European Cardiology Review, 2(1), 15.
2. J Lehman (2009). Operational Organich Chemistry. Operational Organich Chemistry
3. L Klampfer,Jörg,W Hans-Georg,D Stephen,Blood (1999). Unknown Title. PMID, 93(7), 94.
4. Colin Rae,Susana Langa,Steven Tucker,David Macewan (2007). Elevated NF-κB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis. Proceedings of the National Academy of Sciences, 104(31), 12790-12795.
5. L Stark (2007). Unknown Title. Carcinogenesis, 28(5), 968.
6. Schwenger,Y Edward,Jan (1996). Unknown Title. The Journal of Biological Chemistry, 8089.
7. J Samson (2012). Correction. PMLA/Publications of the Modern Language Association of America, 127(3), 432-432.
8. R Morrison,R Boyed (1973). Organic Chemistry. Organic Chemistry, 3
9. Al-Abachi Mq,Al-Delami Ams,Al-Najafi As (1988). Unknown Title. Analyst, 1661.
10. J Roberts,M Caserio (1964). Basic Principles of Organic Chemistry. Basic Principles of Organic Chemistry
11. M Al-Rufaie,W (2016). Unknown Title. J. of pharmacy and pharmaceutical sciences, 5(3), 172.
12. Abdul Satar (2006). Unknown Title.
13. M Al-Rufaie,A Al-Sharefy,K Kathem (2013). Unknown Title. H. J. of Applicable Chemistry, 2(4), 931.
14. K Rathod,N Thakre (2013). Synthesis and Antimicrobial Activity of Azo Compounds Containing m-Cresol Moiety. Chemical Science Transactions, 2(1), 25-28.
15. D Marmion (1999). Hand book of colorant. Hand book of colorant
16. M Al-Rufaie,A Al-Sharefy,K Inter (2013). Unknown Title. J. of Uni. Pharmacy and Bio Sciences, 2(4), 2319.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Mohauman Mohammad Al-Rufaie. 2016. "Spectrophotometric Determination of Sodium Salicylate in Pharmaceutical Preparations by Coupling with Diazotized Paraamino Benzoic Acid". Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 16 (GJSFR Volume 16 Issue B3).

More Citation Formats

Select Citation Style:

Download Citation

GJSFR Volume 16 Issue B3

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

Not Found

Classification

GJSFR-B Classification FOR Code: 030599

Submission ReceivedJuly 3, 2016
Peer Review Double Blind
Handling Editor
Accepted July 26, 2016
Published August 5, 2016

Version of record

v1.2

Issue date

October 12, 2016

Language

English

Order Article Reprint

Experience in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Score: 101

Country: Iraq

Subject: Global Journal of Science Frontier Research - B: Chemistry

Authors: Mohauman Mohammad Al-Rufaie (PhD/Dr. count: 0)

View Count (all-time): 403

Total Views (Real + Logic): 1653

Total Downloads (simulated): 121

Publish Date: 2016 08, Fri

Monthly Totals (Real + Logic):

Month 1: 27 views
Month 2: 44 views
Month 3: 37 views
Month 4: 33 views
Month 5: 59 views
Month 6: 23 views
Month 7: 29 views
Month 8: 45 views
Month 9: 26 views
Month 10: 46 views
Month 11: 36 views
Month 12: 49 views
Month 13: 26 views
Month 14: 48 views
Month 15: 47 views
Month 16: 41 views
Month 17: 29 views
Month 18: 23 views
Month 19: 34 views
Month 20: 23 views
Month 21: 24 views
Month 22: 12 views
Month 23: 31 views
Month 24: 44 views
Month 25: 33 views
Month 26: 31 views
Month 27: 29 views
Month 28: 18 views
Month 29: 21 views
Month 30: 30 views
Month 31: 34 views
Month 32: 33 views
Month 33: 25 views
Month 34: 22 views
Month 35: 19 views
Month 36: 24 views
Month 37: 31 views
Month 38: 24 views
Month 39: 37 views
Month 40: 40 views
Month 41: 44 views
Month 42: 31 views
Month 43: 24 views
Month 44: 37 views
Month 45: 30 views
Month 46: 24 views
Month 47: 36 views
Month 48: 30 views
Month 49: 24 views
Month 50: 30 views
Month 51: 42 views
Month 52: 37 views
Month 53: 22 views
Month 54: 25 views
Month 55: 37 views
Month 56: 25 views
Month 57: 34 views
Month 58: 29 views
Month 59: 19 views
Month 60: 37 views
Month 61: 34 views
Month 62: 22 views
Month 63: 36 views
Month 64: 14 views
Month 65: 16 views
Month 66: 36 views
Month 67: 38 views
Month 68: 24 views
Month 69: 45 views
Month 70: 35 views
Month 71: 15 views
Month 72: 11 views
Month 73: 37 views
Month 74: 19 views
Month 75: 24 views
Month 76: 29 views
Month 77: 13 views
Month 78: 41 views
Month 79: 29 views
Month 80: 31 views
Month 81: 34 views
Month 82: 31 views
Month 83: 33 views
Month 84: 45 views
Month 85: 45 views
Month 86: 26 views
Month 87: 18 views
Month 88: 36 views
Month 89: 36 views
Month 90: 26 views
Month 91: 37 views
Month 92: 22 views
Month 93: 25 views
Month 94: 29 views
Month 95: 22 views
Month 96: 28 views
Month 97: 45 views
Month 98: 31 views
Month 99: 20 views
Month 100: 39 views
Month 101: 34 views
Month 102: 34 views
Month 103: 13 views
Month 104: 38 views
Month 105: 49 views
Month 106: 22 views
Month 107: 18 views
Month 108: 28 views
Month 109: 29 views
Month 110: 38 views
Month 111: 47 views
Month 112: 26 views
Month 113: 47 views
Month 114: 38 views
Month 115: 23 views
Month 116: 60 views
Month 117: 32 views
Month 118: 39 views
Month 119: 43 views
Month 120: 73 views
Month 121: 50 views
Month 122: 67 views
Month 123: 51 views

Total Views: 1.7K

Total Downloads: 121

All Trends