Synthesis and Chemistry of Bis-imidazole Derivatives: A Review

§ Helwan University

Send Message

To: Author

Synthesis and Chemistry of Bis-imidazole Derivatives: A Review

Article Fingerprint

ReserarchID

XE7GK

Synthesis and Chemistry of Bis-imidazole Derivatives: A Review Banner

Key Research Insights

Synthesized scholarly intelligence & interactive research assistant
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu
Reading Preferences
Font Size
Line Spacing
Background
This converted HTML version may contain rendering inconsistencies. Please refer to the PDF for the authoritative version, or click here to provide feedback.

Abstract

Imidazole, an important heterocycle, having biological and therapeutic properties prompted various medicinal chemists to develop various synthetic methods to synthesize a large number of novel derivatives used in chemotherapy. This fascinating group of heterocyclic compounds has interesting biological activities such as antimicrobial, anticancer, antiviral, analgesic, anti-inflammatory, anthelmintic, anticonvulsant, antiulcer, and anti-allergic activity. Various bis-imidazole derivatives introduced a great contribution not only in the field of synthetic organic chemistry but also in the field of medicinal chemistry and chemotherapy. This article aims to review the work reported in the synthesis and chemistry of bis-imidazole derivatives during past years.

References

26 Cites in Article
  1. 1. Deepika Sharma,Balasubramanian Narasimhan,Pradeep Kumar,Vikramjeet Judge,Rakesh Narang,Erik De Clercq,Jan Balzarini (2009). Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives. European Journal of Medicinal Chemistry, 44(6), 2347-2353.
  2. 2. P Manocha,A Sr Wakode,K Kaur,H Anand,Kumar (2016). Unknown Title. International Journal of Pharmaceutical Science and Research, 12-16.
  3. 3. Y Ozkay,I Iskar,Z Incesu,Akalın Ge (2010). Unknown Title. European Journal of Medicinal Chemistry, 1-9.
  4. 4. M.-M Luo,S.-J Guo,C.-H Zhou,R.-G Xie (1995). Unknown Title. Heterocycles, 41, 1421.
  5. 5. F Hadizadeh,H Hosseinzadeh,Sadat Motamed-Shariaty,V Seifi,M Kazemi,S (2008). Unknown Title. Iranian Journal of Pharmaceutical Research, 7(1), 29-33.
  6. 6. A Katritzky (1984). Unknown Title. Rees. Comprehensive Heterocyclic Chemistry, 5, 469-498.
  7. 7. M Grimmett (1997). Introduction. Imidazole and Benzimidazole Synthesis, 1-2.
  8. 8. E Brown (1998). Ring Nitrogen and Key Biomolecules. Ring Nitrogen and Key Biomolecules
  9. 9. A Pozharskii (1997). Heterocycles in Life and Society. Heterocycles in Life and Society
  10. 10. Rakesh Chawla,Suresh Kumar,Anupam Sharma (2012). The genus Clematis (Ranunculaceae): Chemical and pharmacological perspectives. Journal of Ethnopharmacology, 143(1), 116-150.
  11. 11. Li-Hui Zhang,Ying-Ying Liu,Jian-Fang Ma,Jin Yang,Li-Guang Zhang,Jun Li,Yan-Wei Li (2011). Syntheses, structures and photoluminescence of a series of coordination frameworks based on dicarboxylate anion and bis(imidazole) ligand. Polyhedron, 30(5), 764-777.
  12. 12. Yue Wang,Fang-Hua Zhao,Ai-Hua Shi,Yun-Xia Che,Ji-Min Zheng (2012). Magnetic and ferroelectric properties of two Co(II) complexes based on flexible bis(imidazole) ligands. Inorganic Chemistry Communications, 20, 23-26.
  13. 13. M Ghazvini,A Mobinikhaledi (2014). Unknown Title. JOURNAL OF CHEMICAL RESEARCH, 648-650.
  14. 14. A Bhatnagar,P Sharma,N Kumar (2011). Unknown Title. Inter. J. Pharm Tech Res, 3(1), 268-282.
  15. 15. Cheng-He Zhou,Xiao-Rong Gu,Ru-Gang Xie,Meng-Shen Cai (1999). Convenient and Efficient Synthesis for a Series of Ether Bis-Imidazoles and Their Derivatives. Synthetic Communications, 29(7), 1217-1222.
  16. 16. Abdullah Asiri,Khadija Badahdah (2006). Synthesis, photochromic, thermochromic, piezochromic and solvatochromic properties of new bis‐imidazole derived from substituted chlorobenzaldehyds. Pigment & Resin Technology, 35(4), 200-204.
  17. 17. Nassir Al-Mohammed,Yatimah Alias,Zanariah Abdullah,Raied Shakir,Ekhlass Taha,Aidil Hamid (2013). Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides. Molecules, 18(10), 11978-11995.
  18. 18. Marcin Jasiński,Grzegorz Mlostoń,Paulina Mucha,Anthony Linden,Heinz Heimgartner (2007). Synthesis of New Bis‐imidazole Derivatives. Helvetica Chimica Acta, 90(9), 1765-1780.
  19. 19. R Bhalla,M Helliwell,C Garner (1996). Unknown Title. Chem. Commun, 921-922.
  20. 20. Rajiv Bhalla,Madeleine Helliwell,C Garner (1997). Synthesis and Coordination Chemistry of the Bis(imidazole) Ligand, Bis(1-methyl-4,5-diphenylimidaz-2-oyl)(benzyloxy)methane. Inorganic Chemistry, 36(14), 2944-2949.
  21. 21. Timothy Higgs,Madeleine Helliwell,C Garner (1996). Synthesis of sterically hindered bis(imidazole) proligands and an exploration of their co-ordination chemistry with copper(II). Journal of the Chemical Society, Dalton Transactions, 2101.
  22. 22. Daniele Zampieri,Maria Mamolo,Luciano Vio,Elena Banfi,Giuditta Scialino,Maurizio Fermeglia,Marco Ferrone,Sabrina Pricl (2007). Synthesis, antifungal and antimycobacterial activities of new bis-imidazole derivatives, and prediction of their binding to P45014DM by molecular docking and MM/PBSA method. Bioorganic & Medicinal Chemistry, 15(23), 7444-7458.
  23. 23. Alexander Wiznycia,Jeremy Rush,Paul Baures (2004). Synthesis of Symmetric Bis(imidazole-4,5-dicarboxamides) Substituted with Amino Acids. The Journal of Organic Chemistry, 69(24), 8489-8491.
  24. 24. M Tian,C Wang,L Wang,K Luo,A Zhao,C Guo (2014). Unknown Title.
  25. 25. Feng Gao,Xing Chen,Feng Zhou,Li-Ping Weng,Li-Tian Guo,Meng Chen,Hui Chao,Liang-Nian Ji (2009). pH responsive luminescent switches of ruthenium(II) complexes containing two imidazole groups: Synthesis, spectroscopy, electrochemistry and theoretical calculations. Inorganica Chimica Acta, 362(14), 4960-4966.
  26. 26. Liang Zhang,Fang Liu (2017). Synthesis of Bisimidazole Derivatives for Selective Sensing of Fluoride Ion. Molecules, 22(9), 1519.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Abdullah Elmorsy. 2018. "Synthesis and Chemistry of Bis-imidazole Derivatives: A Review". Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 18 (GJSFR Volume 18 Issue B1).

More Citation Formats

Download Citation

Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords
Classification
GJSFR-B Classification FOR Code: 039999
Version of record

v1.2

Issue date
April 2, 2018

Language
English
Order Article Reprint
Experience in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

Article Matrices
Total Views: 1.4K
Total Downloads: 94
All Trends

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

Synthesis and Chemistry of Bis-imidazole Derivatives: A Review

Abdullah Elmorsy
Abdullah Elmorsy Helwan University