Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One

α
Chalak Azimi
Chalak Azimi
σ
Helal Tahazadeh
Helal Tahazadeh
ρ
Rasol Kamari
Rasol Kamari
α Islamic Azad University, Tehran Islamic Azad University, Tehran

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Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One

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Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One Banner

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Abstract

4-propionyl-3-(4-substitutedphenylamino) isoxazol-5(2H)-one, substituted on nitrogen with a 2-chlorobenzot-hiazole group, reacts with triethylamine (TEA) in ethanol under reflux conditions to provide a convenient synthesis of 1-(2-(4-substitutedphenyl amino) -imidazo [2,1b] benzothiazole-3-yl) propan-1-one.

References

33 Cites in Article
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  10. (2-(4-bromophenylamino)-imidazo[2,1-b] benzothiazole-3-yl) propan-1-one (15, X.
  11. mmol) and triethylamine (0.3 mL) were refluxed in ethanol (10 mL) for 24 hours. The reaction mixture was left to cool to room tempreture and resulting precipitate was colleted to afford 1-(2-(4-bromophenylamino)imidazo [2, 1-b] benzothiazole-3-yl) propan-1-one as white needles.
  12. (null). Figure 2—figure supplement 1. 1H and 13C NMR spectra of compound 3..
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  15. Manfred Wildner (2022). COVID-19: Resilienz, nicht Resignation.
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  20. Chen-Jiang Liu,Chuan-Ji Yu (2010). An Efficient Synthesis of 1-Aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one Catalyzed by a Brønsted Acid Ionic Liquid.
  21. mmol) and triethylamine (0.3 mL) were refluxed in ethanol (10 mL) for 24 hours. The reaction mixture was left to cool to room tempreture and resulting precipitate was colleted to afford 1-(2-(4-nitrophenylamino)-imidazo.
  22. C (null). Enhanced Method for the Synthesis and Comprehensive Characterization of 1(4-Phenylquinolin-2-yl)propan-1-one.
  23. 6 -DMSO)(δppm): 1.18.
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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Chalak Azimi. 2014. \u201cSynthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 14 (GJSFR Volume 14 Issue B2): .

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Issue Cover
GJSFR Volume 14 Issue B2
Pg. 51- 56
Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Version of record

v1.2

Issue date

May 28, 2014

Language
en
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4-propionyl-3-(4-substitutedphenylamino) isoxazol-5(2H)-one, substituted on nitrogen with a 2-chlorobenzot-hiazole group, reacts with triethylamine (TEA) in ethanol under reflux conditions to provide a convenient synthesis of 1-(2-(4-substitutedphenyl amino) -imidazo [2,1b] benzothiazole-3-yl) propan-1-one.

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Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One

Chalak Azimi
Chalak Azimi
Helal Tahazadeh
Helal Tahazadeh
Rasol Kamari
Rasol Kamari

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