Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants

Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants

paula_david

Contact

Paula David

Contact

Abdulla Watad

Contact

Gilad Halpert

Contact

Yehuda Shoenfeld

Contact

Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants

Article Fingerprint

ReserarchID

6558G

Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants Banner

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

Autoimmune/Inflammatory Syndromes Induced by Adjuvants (ASIA) syndrome is a group of immune-mediated disorders and symptoms that may appear in genetically predisposed individuals after environmental exposure to external factors, the adjuvants, such as silicone, aluminium and other metals. Sarcoidosis, one of its classic examples, have been previously described following tattoo. However, tattoo ink is still not recognized as one of the adjuvants capable of triggering the ASIA syndrome. To reinforce our theory, we also described a 32-yearold patient that developed arthralgia, sicca syndrome, small fiber neuropathy, and post orthostatic tachycardia syndrome (POTS) after being exposed to extensive areas of tattoos and propose the tattoo ink as a possible trigger for the ASIA syndrome, questioning its safety in individuals genetically prone for autoimmunity.

References

47 Cites in Article

Reference Format

Y Shoenfeld,N Agmon-Levin (2011). ASIA"autoimmune/inflammatory syndrome induced by adjuvants.
V Molina,Y Shoenfeld (2005). Infection, vaccines and other environmental triggers of autoimmunity.
R Inbar,R Weiss,L Tomljenovic,M-T Arango,Y Deri,C Shaw,J Chapman,M Blank,Y Shoenfeld (2017). Behavioral abnormalities in female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil.
Agmon-Levin Nancy,Yehuda Shoenfeld (2008). Chronic fatigue syndrome with autoantibodies — The result of an augmented adjuvant effect of hepatitis-B vaccine and silicone implant.
P Kagan,G Halpert,H Amital,R Shapira,Y Shoenfeld (2020). Autoimmune/Inflammatory Syndrome Induced by Adjuvant Associated with a Metal Implant in the Mouth; Explantation Was Followed by Recovery.
Ariel Schiff,Nizar Jiries,Shaul Goldsztein,Elad Schiff,Shira Ginsberg (2020). A possible association of orthopedic metal implants and ASIA syndrome.
Abdulla Watad,Kassem Sharif,Yehuda Shoenfeld (2017). The ASIA syndrome: basic concepts.
A Watad,M Quaresma,S Brown,J Cohen Tervaert,I Rodríguez-Pint,R Cervera,C Perricone,Y Shoenfeld (2017). Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld’s syndrome) – An update.
Vânia Borba,Anna Malkova,Natalia Basantsova,Gilad Halpert,Laura Andreoli,Angela Tincani,Howard Amital,Yehuda Shoenfeld (2020). Classical Examples of the Concept of the ASIA Syndrome.
Jorge Cárdenas-Roldán,Adriana Rojas-Villarraga,Juan-Manuel Anaya (2013). How do autoimmune diseases cluster in families? A systematic review and meta-analysis.
Sophie Steiner,Sonya Becker,Jelka Hartwig,Franziska Sotzny,Sebastian Lorenz,Sandra Bauer,Madlen Löbel,Anna Stittrich,Patricia Grabowski,Carmen Scheibenbogen (2020). Autoimmunity-Related Risk Variants in PTPN22 and CTLA4 Are Associated With ME/CFS With Infectious Onset.
Xavier Mariette,Lindsey Criswell (2018). Primary Sjögren’s Syndrome.
N Kluger (2018). Tattoo‐associated uveitis with or without systemic sarcoidosis: a comparative review of the literature.
Koichi Izumikawa,Noriko Motoi,Hisashi Takaya,Atsushi Miyamoto,Yoshinobu Eishi,Kunihiko Yoshimura,Kazuma Kishi (2011). A Case of Concurrent Sarcoidosis, Aortitis Syndrome and Crohn's Disease.
L Torres,S Faiz (2014). Tattoos and Sarcoidosis.
Sara Bindoli,A Dagan,J Torres-Ruiz,C Perricone,M Bizjak,Doria Shoenfeld,Y (2016). SARCOIDOSIS AND AUTOIMMUNITY: FROM GENETIC BACKGROUND TO ENVIRONMENTAL FACTORS.
Dominique Valeyre,Antje Prasse,Hilario Nunes,Yurdagul Uzunhan,Pierre-Yves Brillet,Joachim Müller-Quernheim (2014). Sarcoidosis.
J Orellana Rios,J Verdaguer Díaz,J Agee,R Theodore Smith (2018). Tattoo associated retinochoroiditis.
Aneta Klímová,Michaela Brichová,Eva Říhová,Jarmila Heissigerová,Petra Svozílková (2017). Immune-Mediated Intraocular Inflammation. Review.
M Moschos,Y Guex-Crosier (2004). Retinal Vasculitis and Cystoid Macular Edema after Body Tattooing: a Case Report.
Ashvini Reddy,Yevgeniy Shildkrot,Steven Newman,Jennifer Thorne (2015). T-Lymphocyte Predominance and Cellular Atypia in Tattoo-Associated Uveitis.
R Sheldon,Grubb Bp 2nd,B Olshansky (2015). 2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope.
Eduardo Benarroch (2012). Postural Tachycardia Syndrome: A Heterogeneous and Multifactorial Disorder.
Hongliang Li,Xichun Yu,Campbell Liles,Muneer Khan,Megan Vanderlinde‐wood,Allison Galloway,Caitlin Zillner,Alexandria Benbrook,Sean Reim,Daniel Collier,Michael Hill,Satish Raj,Luis Okamoto,Madeleine Cunningham,Christopher Aston,David Kem (2014). Autoimmune Basis for Postural Tachycardia Syndrome.
W Gunning 3rd,H Kvale,P Kramer,B Karabin,B Grubb (2019). Postural Orthostatic Tachycardia Syndrome Is Associated With Elevated G-Protein Coupled Receptor Autoantibodies.
Artur Fedorowski,Hongliang Li,Xichun Yu,Kristi Koelsch,Valerie Harris,Campbell Liles,Taylor Murphy,Syed Quadri,Robert Scofield,Richard Sutton,Olle Melander,David Kem (2017). Antiadrenergic autoimmunity in postural tachycardia syndrome.
D Dubey,S Hopkins,S Vernino (2016). M1 and M2 muscarinic receptor antibodies among patients with postural orthostatic tachycardia syndrome: potential disease biomarker.
Carl‐albrecht Haensch,Marco Tosch,Istvan Katona,Joachim Weis,Stefan Isenmann (2014). Small‐fiber neuropathy with cardiac denervation in postural tachycardia syndrome.
V Iodice,D Low,C Mathias,P Facer,Y Yiangou,P Anand (2015). Small fibre neuropathy and collagen IV reduction in postural tachycardia syndrome and joint hypermobility syndrome.
Parvez Islam,Christopher Chang,Carlo Selmi,Elena Generali,Arthur Huntley,Suzanne Teuber,M Gershwin (2016). Medical Complications of Tattoos: A Comprehensive Review.
Yehuda Shoenfeld,Varvara Ryabkova,Carmen Scheibenbogen,Louise Brinth,Manuel Martinez-Lavin,Shuichi Ikeda,Harald Heidecke,Abdulla Watad,Nicola Bragazzi,Joab Chapman,Leonid Churilov,Howard Amital (2020). Complex syndromes of chronic pain, fatigue and cognitive impairment linked to autoimmune dysautonomia and small fiber neuropathy.
Kyungpyo Park,Rainer Haberberger,Tom Gordon,Michael Jackson (2011). Antibodies interfering with the type 3 muscarinic receptor pathway inhibit gastrointestinal motility and cholinergic neurotransmission in Sjögren's syndrome.
O Malysheva,M Pierer,U Wagner,M Wahle,U Wagner,C Baerwald (2008). Association between β2 adrenergic receptor polymorphisms and rheumatoid arthritis in conjunction with human leukocyte antigen (HLA)-DRB1 shared epitope.
Krystian Jazdzewski,Tomasz Bednarczuk,Magdalena Stepnowska,Sandya Liyanarachchi,Krystyna Suchecka-Rachon,Janusz Limon,Krzysztof Narkiewicz (2007). β-2-Adrenergic receptor gene polymorphism confers susceptibility to Graves disease.
J V Metcalf,R Bhopal,J Gray,D Howel,O James (1997). Incidence and prevalence of primary biliary cirrhosis in the city of Newcastle upon Tyne, England.
Otavio Cabral-Marques,Alexandre Marques,Lasse Giil,Roberta De Vito,Judith Rademacher,Jeannine Günther,Tanja Lange,Jens Humrich,Sebastian Klapa,Susanne Schinke,Lena Schimke,Gabriele Marschner,Silke Pitann,Sabine Adler,Ralf Dechend,Dominik Müller,Ioana Braicu,Jalid Sehouli,Kai Schulze-Forster,Tobias Trippel,Carmen Scheibenbogen,Annetine Staff,Peter Mertens,Madlen Löbel,Justin Mastroianni,Corinna Plattfaut,Frank Gieseler,Duska Dragun,Barbara Engelhardt,Maria Fernandez-Cabezudo,Hans Ochs,Basel Al-Ramadi,Peter Lamprecht,Antje Mueller,Harald Heidecke,Gabriela Riemekasten (2018). GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis.
B Xu,D Huang,R Pirskanen,A Lefvert (2000). beta2-adrenergic receptor gene polymorphisms in myasthenia gravis (MG).
Anthony Smith,Michael Jackson,Fang Wang,Dana Cavill,Maureen Rischmueller,Tom Gordon (2005). Neutralization of Muscarinic Receptor Autoantibodies by Intravenous Immunoglobulin in Sjögren Syndrome.
Olga Vera-Lastra,Eduardo Rojas-Milán,Ana Peralta-Amaro,Magdalena Sánchez-Uribe,Leopoldo Cruz-González,Mario Hernández-Sánchez,Laura Tecayehuatl-Negrete,María Cruz-Dominguez,Luis Jara (2020). Autoimmune/inflammatory syndrome induced by methylmethacrylate associated to seronegative antiphospholipid syndrome and diffuse large B-cell non-Hodgkin’s lymphoma.
Alberto Goldman,Uwe Wollina (2019). Polymethylmethacrylate-induced nodules of the lips: Clinical presentation and management by intralesional neodymium:YAG laser therapy.
A Goldman,H Staub,U Wollina (2018). HYPERCALCEMIA DUE TO POLYMETHYLMETHACRYLATE INJECTIONS? (LITERATURE REVIEW AND CASE REPORTS).
Alberto Goldman,Uwe Wollina (2018). Intralesional Neodymium YAG laser to Treat Complications of Polymethylmethacrylate.
Keun Ahn,Zhenlong Zheng,Tae Kwon,Beom Kim,Hye Lee,Sung Cho (2017). Pattern analysis of laser-tattoo interactions for picosecond- and nanosecond-domain 1,064-nm neodymium-doped yttrium-aluminum-garnet lasers in tissue-mimicking phantom.
N Khunger,A Molpariya,A Khunger (2015). Complications of Tattoos and Tattoo Removal: Stop and Think Before you ink.
Maartje Colaris,Mintsje De Boer,Rene Van Der Hulst,Jan Cohen Tervaert (2017). Two hundreds cases of ASIA syndrome following silicone implants: a comparative study of 30 years and a review of current literature.
Trucian Ostheimer,Bryn Burkholder,Theresa Leung,Nicholas Butler,James Dunn,Jennifer Thorne (2014). Tattoo-Associated Uveitis.
Luísa Guimarães,Britain Baker,Carlo Perricone,Yehuda Shoenfeld (2015). Vaccines, adjuvants and autoimmunity.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

paula_david. 2021. \u201cTattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 21 (GJMR Volume 21 Issue F1): .

More Citation Formats

Select Citation Style:

Download Citation

Download Article

GJMR Volume 21 Issue F1
Pg. 47- 52

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

Not Found

Classification

GJMR-F Classification: NLMC Code: WD 305

Submission ReceivedFebruary 13, 2021
Peer Review Double Blind
Handling Editor
Accepted March 4, 2021
Published March 15, 2021

Version of record

v1.2

Issue date

March 28, 2021

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Views: 2044

Total Downloads: 960

2026 Trends

Published Article

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]