Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants

Paula David; Abdulla Watad; Gilad Halpert; Yehuda Shoenfeld

Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants

Paula David *

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Abdulla Watad

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Gilad Halpert

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Yehuda Shoenfeld

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Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants

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Abstract

Autoimmune/Inflammatory Syndromes Induced by Adjuvants (ASIA) syndrome is a group of immune-mediated disorders and symptoms that may appear in genetically predisposed individuals after environmental exposure to external factors, the adjuvants, such as silicone, aluminium and other metals. Sarcoidosis, one of its classic examples, have been previously described following tattoo. However, tattoo ink is still not recognized as one of the adjuvants capable of triggering the ASIA syndrome. To reinforce our theory, we also described a 32-yearold patient that developed arthralgia, sicca syndrome, small fiber neuropathy, and post orthostatic tachycardia syndrome (POTS) after being exposed to extensive areas of tattoos and propose the tattoo ink as a possible trigger for the ASIA syndrome, questioning its safety in individuals genetically prone for autoimmunity.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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How to Cite This Article

Paula David, Abdulla Watad, Gilad Halpert, Yehuda Shoenfeld. 2021. "Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants". Global Journal of Medical Research - F: Diseases GJMR-F Volume 21 (GJMR Volume 21 Issue F1).

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GJMR Volume 21 Issue F1

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification NLMC Code: WD 305

Submission ReceivedFebruary 13, 2021
Peer Review Double Blind
Handling Editor
Accepted March 4, 2021
Published March 15, 2021

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v1.2

Issue date

March 28, 2021

Language

English

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