The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

1
Aykut Soyder
Aykut Soyder
2
Mustafa  AonAbol
Mustafa AonAbol
3
Serdar AzbaA
Serdar AzbaA
4
SavaA KoAak
SavaA KoAak
1 Adnan Menderes University Medical Faculty, Department of General Surgery, 09100 AydAn, Turkey

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The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease Banner
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Background: The presence of hypoactive nodules in patients with Graves’ disease (GD) is an important factor in deciding on surgical treatment. Literatures are inconclusive about the increase in the risk of malignancy in cases of hypoactive nodules accompanying GD. The incidence of incidental malignancy in patients that underwent surgical treatment for GD were evaluated. Materials and Methods: This study included 108 patients that underwent thyroidectomy due to GD. Hypoactive nodules and diffuse hyperplasia were observed in 59 (54.6%) and 49 (45,4%) of the patients, respectively, during preoperative evaluation. In all 108 patients total thyroidectomy (TT) was the preferred surgical method. Results: Malignant histopathology was noted in 11 (10.2%) of the 108 patients. The thyroid nodules preoperatively observed in 59 patients were determined to be benign according to fine needle aspiration biopsy (FNAB), which also showed that 7 (11.9%) patients had incidental malignancy.

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Aykut Soyder. 2014. \u201cThe Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease\u201d. Unknown Journal GJMR-I Volume 14 (GJMR Volume 14 Issue I3): .

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August 29, 2014

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Background: The presence of hypoactive nodules in patients with Graves’ disease (GD) is an important factor in deciding on surgical treatment. Literatures are inconclusive about the increase in the risk of malignancy in cases of hypoactive nodules accompanying GD. The incidence of incidental malignancy in patients that underwent surgical treatment for GD were evaluated. Materials and Methods: This study included 108 patients that underwent thyroidectomy due to GD. Hypoactive nodules and diffuse hyperplasia were observed in 59 (54.6%) and 49 (45,4%) of the patients, respectively, during preoperative evaluation. In all 108 patients total thyroidectomy (TT) was the preferred surgical method. Results: Malignant histopathology was noted in 11 (10.2%) of the 108 patients. The thyroid nodules preoperatively observed in 59 patients were determined to be benign according to fine needle aspiration biopsy (FNAB), which also showed that 7 (11.9%) patients had incidental malignancy.

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The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

Aykut Soyder
Aykut Soyder Adnan Menderes University Medical Faculty, Department of General Surgery, 09100 AydAn, Turkey
Mustafa  AonAbol
Mustafa AonAbol
Serdar AzbaA
Serdar AzbaA
SavaA KoAak
SavaA KoAak

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