The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

Aykut Soyder

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Mustafa AonAbol

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Serdar AzbaA

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SavaA KoAak

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Adnan Menderes University

The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

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Abstract

Background: The presence of hypoactive nodules in patients with Graves’ disease (GD) is an important factor in deciding on surgical treatment. Literatures are inconclusive about the increase in the risk of malignancy in cases of hypoactive nodules accompanying GD. The incidence of incidental malignancy in patients that underwent surgical treatment for GD were evaluated. Materials and Methods: This study included 108 patients that underwent thyroidectomy due to GD. Hypoactive nodules and diffuse hyperplasia were observed in 59 (54.6%) and 49 (45,4%) of the patients, respectively, during preoperative evaluation. In all 108 patients total thyroidectomy (TT) was the preferred surgical method. Results: Malignant histopathology was noted in 11 (10.2%) of the 108 patients. The thyroid nodules preoperatively observed in 59 patients were determined to be benign according to fine needle aspiration biopsy (FNAB), which also showed that 7 (11.9%) patients had incidental malignancy.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Aykut Soyder. 2014. \u201cThe Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease\u201d. Unknown Journal GJMR-I Volume 14 (GJMR Volume 14 Issue I3).

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Journal Specifications

Keywords

grave’s disease incidental thyroid cancer surgical treatment thyroid nodule

Submission ReceivedDecember 9, 2013
Peer Review Double Blind
Handling Editor
Accepted January 3, 2014
Published January 15, 2014

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v1.2

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August 29, 2014

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Article Matrices

Total Score: 104

Country: Turkey

Subject: Uncategorized

Authors: Aykut Soyder, Mustafa AonAbol, Serdar AzbaA, SavaA KoAak (PhD/Dr. count: 0)

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