The Importance of Diagnosis and Specialized Treatment in Merkel Cell Carcinoma: Case Report in a Young Healthy Woman, Literature Review and Brief Update on Approach

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Liliane Cristina Da Silva
Liliane Cristina Da Silva
α Universidade de São Paulo Universidade de São Paulo

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The Importance of Diagnosis and Specialized Treatment in Merkel Cell Carcinoma: Case Report in a Young Healthy Woman, Literature Review and Brief Update on Approach

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Abstract

Merkel Cell Carcinoma (MCC) is extremely rare and aggressive, with an overall survival of 40% in 5 years. The non-oncological physician has large difficulty about the correct approach of this pathology. We report the sixth case of MCC in a young healthy patient (woman, 19 years old) described in the medical literature, who was treated twice for sebaceous cyst, evolved with local disease progression, needed a larger resection and, after adjuvant therapy, remains no tumor recurrence. Despite being an extremely rare neoplasm, therapeutics should not be underestimated by non-oncological physician because this cancer is too aggressive, and the correct oncological approach could result in increased progression-free survival for these patients.

References

9 Cites in Article
  1. Alfredo Vitototo,Colapietra Upper eyelid Merkel cell carcinoma treated with neoadjuvant chemotherapy and surgical excision.
  2. Paul Harms (2017). Update on Merkel Cell Carcinoma.
  3. Drew Emge,Adela Cardones (2019). Updates on Merkel Cell Carcinoma.
  4. Thibault Kervarrec,Mahtab Samimi,Serge Guyétant,Bhavishya Sarma,Jérémy Chéret,Emmanuelle Blanchard,Patricia Berthon,David Schrama,Roland Houben,Antoine Touzé (2019). Histogenesis of Merkel Cell Carcinoma: A Comprehensive Review.
  5. Michael Cardis (2019). Diffuse lichen planus-like keratoses and clinical pseudo-progression associated with avelumab treatment for Merkel cell carcinoma, a case report.
  6. S Roy,I Das,A Nandi,R Roy (2015). Primary Merkel cell carcinoma of the oral mucosa in a young adult male: Report of a rare case.
  7. Teresa Amaral,Ulrike Leiter,Claus Garbe (2017). Merkel cell carcinoma: Epidemiology, pathogenesis, diagnosis and therapy.
  8. Non Ha,Sue Kim,Yoo Shin,Sue Kim (2018). Primary Merkel cell carcinoma of the earlobe in a young healthy man.
  9. S Prabhu,R Smitha,V Punnya (2009). of Diagnosis and Specialized Treatment in Merkel Cell Carcinoma: Case Report in a Young Healthy Woman, Literature Review and Brief Update on Approach.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Liliane Cristina Da Silva. 2020. \u201cThe Importance of Diagnosis and Specialized Treatment in Merkel Cell Carcinoma: Case Report in a Young Healthy Woman, Literature Review and Brief Update on Approach\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 20 (GJMR Volume 20 Issue F3): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-F Classification: NLMC Code: WP 460
Version of record

v1.2

Issue date

March 17, 2020

Language
pt, en
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Merkel Cell Carcinoma (MCC) is extremely rare and aggressive, with an overall survival of 40% in 5 years. The non-oncological physician has large difficulty about the correct approach of this pathology. We report the sixth case of MCC in a young healthy patient (woman, 19 years old) described in the medical literature, who was treated twice for sebaceous cyst, evolved with local disease progression, needed a larger resection and, after adjuvant therapy, remains no tumor recurrence. Despite being an extremely rare neoplasm, therapeutics should not be underestimated by non-oncological physician because this cancer is too aggressive, and the correct oncological approach could result in increased progression-free survival for these patients.

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The Importance of Diagnosis and Specialized Treatment in Merkel Cell Carcinoma: Case Report in a Young Healthy Woman, Literature Review and Brief Update on Approach

Liliane Cristina Da Silva
Liliane Cristina Da Silva Universidade de São Paulo

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