THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

1
Dr. Vickram
Dr. Vickram
2
Divya D
Divya D
3
Vijay V
Vijay V
4
Kashinath.R.T
Kashinath.R.T
1 Basaveshwara Medical college & Hospital / Rajiv Gandhi University of Health Sciences

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GJMR Volume 11 Issue 1

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THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER Banner
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Abstracts -Liver glycogen content and liver glycogen synthesis are lowered in diabetes mellitus due to lack of functioning insulin. Many enzymes of glycogen metabolism as well as glucose metabolism are sulfhydryl in nature and are affected by changes in cellular thiol-disulfide ratio. Certain low molecular weight thiols can influence glucose uptake and utilization in fat cells and in muscle cells. A study was undertaken to establish the effect of thiopropanol ( 3-mercapto 1 propanol) on glycogen breakdown in isolated alloxan diabetic liver. The results indicate that thiopropanol influences glycogen breakdown, lactic acid production in alloxan diabetic liver which may be attributed to increased activity of hexokinase in thiopropanol-exposed-alloxan diabetic liver

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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Dr. Vickram. 1970. \u201cTHIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER\u201d. Unknown Journal GJMR Volume 11 (GJMR Volume 11 Issue 1): .

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April 25, 2011

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Abstracts -Liver glycogen content and liver glycogen synthesis are lowered in diabetes mellitus due to lack of functioning insulin. Many enzymes of glycogen metabolism as well as glucose metabolism are sulfhydryl in nature and are affected by changes in cellular thiol-disulfide ratio. Certain low molecular weight thiols can influence glucose uptake and utilization in fat cells and in muscle cells. A study was undertaken to establish the effect of thiopropanol ( 3-mercapto 1 propanol) on glycogen breakdown in isolated alloxan diabetic liver. The results indicate that thiopropanol influences glycogen breakdown, lactic acid production in alloxan diabetic liver which may be attributed to increased activity of hexokinase in thiopropanol-exposed-alloxan diabetic liver

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THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

Dr. Vickram
Dr. Vickram Basaveshwara Medical college & Hospital / Rajiv Gandhi University of Health Sciences
Divya D
Divya D
Vijay V
Vijay V
Kashinath.R.T
Kashinath.R.T

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