THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

Article ID

G1615

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THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

Dr. Vickram Basaveshwara Medical college & Hospital / Rajiv Gandhi University of Health Sciences

Divya D

Vijay V

Kashinath.R.T

DOI

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Abstract

Liver glycogen content and liver glycogen synthesis are lowered in diabetes mellitus due to lack of functioning insulin. Many enzymes of glycogen metabolism as well as glucose metabolism are sulfhydryl in nature and are affected by changes in cellular thiol-disulfide ratio. Certain low molecular weight thiols can influence glucose uptake and utilization in fat cells and in muscle cells. A study was undertaken to establish the effect of thiopropanol ( 3-mercapto 1 propanol) on glycogen breakdown in isolated alloxan diabetic liver. The results indicate that thiopropanol influences glycogen breakdown, lactic acid production in alloxan diabetic liver which may be attributed to increased activity of hexokinase in thiopropanol-exposed-alloxan diabetic liver

THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

Authors

Dr. Vickram Basaveshwara Medical college & Hospital / Rajiv Gandhi University of Health Sciences

Divya D

Vijay V

Kashinath.R.T

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Dr. Vickram. 1970. “. Unknown Journal GJMR Volume 11 (GJMR Volume 11 Issue 1): .

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GJMR Volume 11 Issue 1
Pg. 1- 4

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Submission Received November 17, 2010
Accepted December 9, 2010
Published December 19, 2010

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Total Score: 109

Country: India

Subject: Uncategorized

Authors: Dr. Vickram, Divya D, Vijay V, Kashinath.R.T (PhD/Dr. count: 1)

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Publish Date: 1970 01, Thu

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