THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

Dr. Vickram
Dr. Vickram
Divya D
Divya D
Vijay V
Vijay V
Kashinath.R.T
Kashinath.R.T
Rajiv Gandhi University of Health Sciences

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THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

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Abstract

Abstracts -Liver glycogen content and liver glycogen synthesis are lowered in diabetes mellitus due to lack of functioning insulin. Many enzymes of glycogen metabolism as well as glucose metabolism are sulfhydryl in nature and are affected by changes in cellular thiol-disulfide ratio. Certain low molecular weight thiols can influence glucose uptake and utilization in fat cells and in muscle cells. A study was undertaken to establish the effect of thiopropanol ( 3-mercapto 1 propanol) on glycogen breakdown in isolated alloxan diabetic liver. The results indicate that thiopropanol influences glycogen breakdown, lactic acid production in alloxan diabetic liver which may be attributed to increased activity of hexokinase in thiopropanol-exposed-alloxan diabetic liver

References

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Vickram. 1970. \u201cTHIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER\u201d. Unknown Journal GJMR Volume 11 (GJMR Volume 11 Issue 1).

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v1.2

Issue date
April 25, 2011

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en
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THIOPROPANOL INDUCED CHANGES IN GLYCOGEN BREAKDOWN IN ALLOXAN DIABETIC LIVER

Dr. Vickram
Dr. Vickram <p>Rajiv Gandhi University of Health Sciences</p>
Divya D
Divya D
Vijay V
Vijay V
Kashinath.R.T
Kashinath.R.T

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