Transdermal Buprenorphine Induced Respiratory Acidosis in a Post TKR patient A Rare Case

Transdermal Buprenorphine Induced Respiratory Acidosis in a Post TKR patient A Rare Case

Vishnu S, Sukesh Rao

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Vishnu S

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Sukesh Rao

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A.V. Gurava Reddy

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Arthroplasty Division, Sunshine Hospitals, Secundrabad.

Transdermal Buprenorphine Induced Respiratory Acidosis in a Post TKR patient A Rare Case

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Abstract

Post-operative pain management consists of a cocktail of drugs ranging from Nsaids, Opioids and Non-opioids. Transdermal Buprenorphine patch is commonly used in pain management of post-operative cases, musculoskeletal pain, cancerous and non-tumorous conditions. Buprenorphine is safely used because of its partial intrinsic activity and slow dissociation on Mu (µ) receptor causing prolonged analgesic effect with a ceiling for respiratory depression. Buprenorphine is commonly used in elderly patients and in patients with chronic renal failure. We report a probable case of buprenorphine patch induced respiratory depression and sedation leading to respiratory acidosis. Respiratory acidosis was managed symptomatically with oxygen therapy and removal of transdermal buprenorphine patch lead to the reversal of clinical condition. Awareness of this possible side effect of buprenorphine patch and unwarranted use should be avoided.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Vishnu S, Sukesh Rao. 2018. \u201cTransdermal Buprenorphine Induced Respiratory Acidosis in a Post TKR patient A Rare Case\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 18 (GJMR Volume 18 Issue B1).

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GJMR Volume 18 Issue B1

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

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Classification

GJMR-B Classification NLMC Code: QV 55

Submission ReceivedDecember 14, 2017
Peer Review Double Blind
Handling Editor
Accepted January 2, 2018
Published January 15, 2018

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v1.2

Issue date

March 28, 2018

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Article Matrices

Total Score: 103

Country: India

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Vishnu S, Sukesh Rao, A.V. Gurava Reddy (PhD/Dr. count: 0)

View Count (all-time): 131

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Publish Date: 2018 03, Wed

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Total Views: 3167

Total Downloads: 1599

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