Ultravist Studies on the Histological Patterns of the Kidney of Adult Wistar Rats

Ultravist Studies on the Histological Patterns of the Kidney of Adult Wistar Rats

Kebe, E. Obeten

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Valentine C. Ikamaise

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Theresa B. Ekanem; Kebe E. Obeten

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Gabriel Udo-Affah

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University of Calabar

Ultravist Studies on the Histological Patterns of the Kidney of Adult Wistar Rats

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Abstract

The aim of this study was to assess the effects of ultravist on the histological patterns of the kidney of the Wistar rat. Thirty (30) Wister rats weighing between 182-212kg/BW were divided into three groups of ten (10) animals each. Group A served as the control group, while group B and C served as experimental groups receiving low and high dosage of ultravist (iopromide) which is the Radiographic Contrast Medium (RCM) used for the experiment respectively. Collection of tissues was carried out on rats at intervals of 30 minutes, 60 minutes, 2 hours, 12 hours and 24 hours following administration of RCM on the experimental groups. The sampling from experimental and control groups were carried out simultaneously following administration of low and high dose of RCM to rats from experimental groups. The result obtained for ultravist after one hour administration presented in plates 2 and 4 showed alteration in the high dose animals while plates 3 and 5 showed marked alterations in the cellular morphology of the kidney of the low dose animals.

References

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Kebe, E. Obeten. 2015. \u201cUltravist Studies on the Histological Patterns of the Kidney of Adult Wistar Rats\u201d. Global Journal of Science Frontier Research - C: Biological Science GJSFR-C Volume 15 (GJSFR Volume 15 Issue C2).

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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Classification

GJSFR-C Classification FOR Code: 069999

Submission ReceivedJanuary 30, 2015
Peer Review Double Blind
Handling Editor
Accepted February 24, 2015
Published March 6, 2015

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v1.2

Issue date

May 9, 2015

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Article Matrices

Total Score: 103

Country: Nigeria

Subject: Global Journal of Science Frontier Research - C: Biological Science

Authors: Valentine C. Ikamaise, Theresa B. Ekanem; Kebe E. Obeten, Gabriel Udo-Affah (PhD/Dr. count: 0)

View Count (all-time): 184

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Total Downloads (simulated): 2150

Publish Date: 2015 05, Sat

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Total Views: 4338

Total Downloads: 2150

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