Use of Immunoglobulin G Enriched With IGM + IGA in Primigestant with Septic Shock: Case Report.

1
Jaime A. Machado-Bernal
Jaime A. Machado-Bernal
2
María C. Espinosa-González
María C. Espinosa-González
3
Hernán L. Valle-Calderón
Hernán L. Valle-Calderón
4
Belkis X. Quant-Vergara
Belkis X. Quant-Vergara

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Sepsis is a condition that occurs when the body produces an unbalanced immune response to an infection. Septic shock is the most serious manifestation of this infection, which increases with aggravation of maternal and perinatal morbidity and mortality. Within the pharmacological therapeutic options, the cornerstone of this entity is broad-spectrum antibiotic therapy; however, there are other drugs that can be used as adjuvants in the context of sepsis and among them are immunoglobulins. Currently there is little scientific evidence about the use of immunoglobulins in pregnant patients and in Colombia there is only one case report published so far. The objective of this patient report is to present the case of a primipregnant woman with a pregnancy of 16.3 weeks diagnosed with septic shock who was administered immunoglobulin G enriched with IgM + IgA, which had an excellent response to the established treatment and satisfactory evolution. without presenting maternal or fetal adverse effects to the drug.

Funding

No external funding was declared for this work.

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The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Jaime A. Machado-Bernal. 2026. \u201cUse of Immunoglobulin G Enriched With IGM + IGA in Primigestant with Septic Shock: Case Report.\u201d. Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 22 (GJMR Volume 22 Issue E3): .

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Immunoglobulin G (IgG) case report on septic shock and immune response analysis in septic patients.
Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-E Classification: DDC Code: 616.94 LCC Code: RC182.S4
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v1.2

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November 25, 2022

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English

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Sepsis is a condition that occurs when the body produces an unbalanced immune response to an infection. Septic shock is the most serious manifestation of this infection, which increases with aggravation of maternal and perinatal morbidity and mortality. Within the pharmacological therapeutic options, the cornerstone of this entity is broad-spectrum antibiotic therapy; however, there are other drugs that can be used as adjuvants in the context of sepsis and among them are immunoglobulins. Currently there is little scientific evidence about the use of immunoglobulins in pregnant patients and in Colombia there is only one case report published so far. The objective of this patient report is to present the case of a primipregnant woman with a pregnancy of 16.3 weeks diagnosed with septic shock who was administered immunoglobulin G enriched with IgM + IgA, which had an excellent response to the established treatment and satisfactory evolution. without presenting maternal or fetal adverse effects to the drug.

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Use of Immunoglobulin G Enriched With IGM + IGA in Primigestant with Septic Shock: Case Report.

Jaime A. Machado-Bernal
Jaime A. Machado-Bernal
María C. Espinosa-González
María C. Espinosa-González
Hernán L. Valle-Calderón
Hernán L. Valle-Calderón
Belkis X. Quant-Vergara
Belkis X. Quant-Vergara

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