Use of Intravenous Clonidine Vs Placebo for Prolonging Spinal Anaesthesia

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Dr Prerana Shah
Dr Prerana Shah
2
Prerana Nirav Shah
Prerana Nirav Shah
3
Devanand Pawar
Devanand Pawar

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Use of intravenous clonidine for prolonging spinal anaesthesia with bupivacaine. Background: Several additives like clonidine are added to prolong spinal blockade. We considered using clonidine through intravenous route as it achieves peak plasma concentration more rapidly than oral or intrathecal routes. The aim was to study onset of analgesia and duration of sensory and motor blockade after spinal anaesthesia. Methods: Our study was a double blind prospective randomized controlled type of 100 patients. In clonidine group, intravenous 3 mcg/ kg of Clonidine diluted in 10ml of normal saline was administered after making the patient supine following the spinal blockade. In saline group, intravenous 10 ml of normal saline was administered. Patients were monitored until the sensory block regressed below L1 dermatome and knee flexion had recovered. Heart rate and mean arterial pressure were measured.

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No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Dr Prerana Shah. 2014. \u201cUse of Intravenous Clonidine Vs Placebo for Prolonging Spinal Anaesthesia\u201d. Unknown Journal GJMR-I Volume 14 (GJMR Volume 14 Issue I1): .

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March 29, 2014

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Use of intravenous clonidine for prolonging spinal anaesthesia with bupivacaine. Background: Several additives like clonidine are added to prolong spinal blockade. We considered using clonidine through intravenous route as it achieves peak plasma concentration more rapidly than oral or intrathecal routes. The aim was to study onset of analgesia and duration of sensory and motor blockade after spinal anaesthesia. Methods: Our study was a double blind prospective randomized controlled type of 100 patients. In clonidine group, intravenous 3 mcg/ kg of Clonidine diluted in 10ml of normal saline was administered after making the patient supine following the spinal blockade. In saline group, intravenous 10 ml of normal saline was administered. Patients were monitored until the sensory block regressed below L1 dermatome and knee flexion had recovered. Heart rate and mean arterial pressure were measured.

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Use of Intravenous Clonidine Vs Placebo for Prolonging Spinal Anaesthesia

Prerana Nirav Shah
Prerana Nirav Shah
Devanand Pawar
Devanand Pawar

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