Using Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine

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Walaa Shabana
Walaa Shabana
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Ismail
Ismail
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Hind Mohamed
Hind Mohamed
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Mossad
Mossad
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W.
W.
α Veterinary Serum and Vaccine Research Institute

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Using Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine

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Abstract

The immunity and protective capability produced by vaccines can vary remarkably according to the kinds of adjuvant being used. Through this work three formulae of the inactivated trivalent FMD vaccine (O pan Asia, A Iran O5 , and SAT2 / EGY/2012) were prepared using different adjuvants including Emulsigen ® -D; Montanid ISA 206 and Emulsigen ® -D (ED) with aluminum hydroxide gel (ALOH). All of these vaccine formulae were found to be free from foreign contaminants and safe. Also, each vaccine formula was injected in a separate sheep group and serum samples were collected along 38-week post-vaccination for tracing of antibodies against FMDV serotypes by serum neutralization test (SNT) and enzyme-linked immune sorbent assay (ELISA).

References

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Walaa Shabana. 2018. \u201cUsing Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine\u201d. Global Journal of Medical Research - G: Veterinary Science & Medicine GJMR-G Volume 18 (GJMR Volume 18 Issue G3): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-G Classification: NLMC Code: QW 70
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v1.2

Issue date

December 22, 2018

Language
en
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The immunity and protective capability produced by vaccines can vary remarkably according to the kinds of adjuvant being used. Through this work three formulae of the inactivated trivalent FMD vaccine (O pan Asia, A Iran O5 , and SAT2 / EGY/2012) were prepared using different adjuvants including Emulsigen ® -D; Montanid ISA 206 and Emulsigen ® -D (ED) with aluminum hydroxide gel (ALOH). All of these vaccine formulae were found to be free from foreign contaminants and safe. Also, each vaccine formula was injected in a separate sheep group and serum samples were collected along 38-week post-vaccination for tracing of antibodies against FMDV serotypes by serum neutralization test (SNT) and enzyme-linked immune sorbent assay (ELISA).

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Using Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine

Walaa Shabana
Walaa Shabana Veterinary Serum and Vaccine Research Institute
Ismail
Ismail
Hind Mohamed
Hind Mohamed
Mossad
Mossad
W.
W.

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