Using Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine

Using Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine

Walaa Shabana

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Ismail

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Hind Mohamed

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Mossad

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Veterinary Serum and Vaccine Research Institute

Using Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine

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Abstract

The immunity and protective capability produced by vaccines can vary remarkably according to the kinds of adjuvant being used. Through this work three formulae of the inactivated trivalent FMD vaccine (O pan Asia, A Iran O5 , and SAT2 / EGY/2012) were prepared using different adjuvants including Emulsigen ® -D; Montanid ISA 206 and Emulsigen ® -D (ED) with aluminum hydroxide gel (ALOH). All of these vaccine formulae were found to be free from foreign contaminants and safe. Also, each vaccine formula was injected in a separate sheep group and serum samples were collected along 38-week post-vaccination for tracing of antibodies against FMDV serotypes by serum neutralization test (SNT) and enzyme-linked immune sorbent assay (ELISA).

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Walaa Shabana. 2018. \u201cUsing Emulsigen-D as Recent Adjuvant in Trivalent Foot and Mouth Disease Vaccine\u201d. Global Journal of Medical Research - G: Veterinary Science & Medicine GJMR-G Volume 18 (GJMR Volume 18 Issue G3).

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GJMR Volume 18 Issue G3

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-G Classification NLMC Code: QW 70

Submission ReceivedDecember 8, 2017
Peer Review Double Blind
Handling Editor
Accepted January 5, 2018
Published January 15, 2018

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December 22, 2018

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Article Matrices

Total Score: 105

Country: Egypt

Subject: Global Journal of Medical Research - G: Veterinary Science & Medicine

Authors: Walaa Shabana, Ismail , Hind Mohamed, Mossad, W. (PhD/Dr. count: 0)

View Count (all-time): 170

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Publish Date: 2018 12, Sat

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Total Views: 2843

Total Downloads: 1420

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