Viral Latency, Molecular  Pathogenesis and Malignancy

Viral Latency, Molecular Pathogenesis and Malignancy

Giulio Tarro

Contact

Temple University

Viral Latency, Molecular Pathogenesis and Malignancy

Article Fingerprint

ReserarchID

MR38H

Viral Latency, Molecular Pathogenesis and Malignancy Banner

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

Viruses are a major component of the biosphere, entering cells and genomes to insert their own genetic material. Herpesvirus lies hidden for years in the cells of the nervous system before emerging to cause herpes vesicles at the body surface. In the ‘virosphere’ there are the retroviruses, whose RNA genome can be converted to DNA by the reverse transcriptase enzyme carried in their viral particles, integrating their genes into the host cell genome and becoming one with it. When, for any of a number of reasons, the host immune system undergoes degrees of immunosoppression, the virus can reactivate, replicate, and cause disease. Even when this does not occur, oncogenic virus latency can induce malignancy in host cells.

References

50 Cites in Article

Reference Format

A Baldwin,K Munger (2010). Molecular events associated with human papillomavirus-induced human cancers in Viral Oncology.
N Baranova,M Carbone (2010). Laura Hengehold et Nancy Bauer (dir.). A Companion to Simone de Beauvoir . Hoboken (New Jersey), Wiley Blackwell, coll. « Blackwell Companions to Philosophy », 2017, 530 p..
T Block,A Mehta (2010). Molecular immunobiology of hepatitis B-associated viral cancer in Viral Oncology.
R Boland,L Ricciardiello,A Goel (2010). Involvement of the polyomavirus, JC virus, in colorectal cancer in Viral Oncology.
Robert Bowles,John Blaho (2011). A truncation mutation of the neurovirulence ICP22 protein produced by a recombinant HSV-1 generated by bacterial artificial chromosome technology targets infected cell nuclei.
J Butel (2010). Simian virus 40, human infections, and cancer: emerging concepts and causality considerations in Viral Oncology.
M-H Chang,D-S Chen (2010). Hepatitis B vaccine and hepatocellular carcinoma in Viral Oncology.
J Chen,A Gershon,Z Li,R Gershon,M (2011). Varicella zoster virus (VZV) infects and established latency in enteric neurons.
Gerardo Chowell,Stefano Bertozzi,M Colchero,Hugo Lopez-Gatell,Celia Alpuche-Aranda,Mauricio Hernandez,Mark Miller (2009). Severe Respiratory Disease Concurrent with the Circulation of H1N1 Influenza.
Charles Cobbs (2012). Evolving evidence implicates cytomegalovirus as a promoter of malignant glioma pathogenesis.
Randall Cohrs,Don Gilden (2012). Alphaherpesvirus latency.
W Dar,B Sugden (2010). Epstein-Barr virus as a pathogen.
F Dawood,S Jain,L Finelli (2009). Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans.
G De Falco,C Bellan,S Lazzi,L Leoncini (2010). HIV-related lymphoma in Viral Oncology.
L Ellis,X Dang,Norton Koralnik (2012). Role of agnogene deletion and archetype-like regulatory region in a JCV strain isolated from the brain of a patient with JCV encephalopathy (JCVE).
Martin Enserink,Jon Cohen (2009). The Novel H1N1 Influenza.
C Esposito,Di Spirito,A Cuomo,N (2012). Tracking the 2009 H1N1 influenza virus in the Italian region Campania.
Mark Feitelson,H Reis,J Pan,B Sun (2010). Hepatitis B Virus and Cancer.
Olivera Finn (2008). Cancer Immunology.
G Hayward,J Donald,R Arav-Boger (2010). The role of KSHV in pathogenesis of Kaposi's sarcoma in Viral Oncology.
K Held,T Derfuss (2012). Control of HSV-1 latency in human trigeminal ganglia -current overview.
M Imperiale,D Das (2010). Possible association of BK virus with prostate cancer in Viral Oncology.
Paola Indovina,Eleonora Marcelli,Francesca Pentimalli,Piero Tanganelli,Giulio Tarro,Antonio Giordano (2012). Mass spectrometry‐based proteomics: The road to lung cancer biomarker discovery.
Paola Indovina,Eleonora Marcelli,Pasquale Maranta,Giulio Tarro (2011). Lung Cancer Proteomics: Recent Advances in Biomarker Discovery.
R Katrenellenbogen,D Galloway (2010). Human papillomavirus-associated cancers in Viral Oncology.
Paul Kinchington,William Goins (2011). Varicella zoster virus-induced pain and post-herpetic neuralgia in the human host and in rodent animal models.
Paula Lister,Fiona Reynolds,Roger Parslow,Alex Chan,Mehrengise Cooper,Adrian Plunkett,Shelly Riphagen,Mark Peters (2009). Swine-origin influenza virus H1N1, seasonal influenza virus, and critical illness in children.
S Marriott (2010). Oncogenic potential of the HTLV-1 tax protein in Viral Oncology.
M Matsuoka (2010). Clinical aspects of HTLV-1associated cancer in Viral Oncology.
V Minhas,C Wood (2010). Biology and epidemiology of HHV-8 in Viral Oncology.
David Morens,Jeffery Taubenberger,Anthony Fauci (2009). The Persistent Legacy of the 1918 Influenza Virus.
J Pagano (2010). Molecular pathobiology of EBV infection in Viral Oncology.
Sonia Perez,Eric Von Hofe,Nikoletta Kallinteris,Angelos Gritzapis,George Peoples,Michael Papamichail,Constantin Baxevanis (2010). A new era in anticancer peptide vaccines.
A Rathi,J Pipas (2010). Oncogenic transformation by polyomavirus large T antigen in Viral Oncology.
K Reiss,K Khalili,Del Valle,L (2010). JC virus association with brain tumors: the role of T antigen and insulin-like growth factor 1 in DNA repair fidelity in Viral.
Bernard Roizman,Guoying Zhou,Te Du (2012). Checkpoints in productive and latent infections with herpes simplex virus 1: conceptualization of the issues.
N Sawtell,S Triezenberg,R Thompson (2011). VP16 serine 375 is a critical determinant of herpes simplex virus exit from latency in vivo.
L Schiller (2008). Noninvasive Monitoring of Tumors.
D Sir,J-H J Ou (2010). Molecular Mechanisms of hepatitis C virus-induced cellular transformation in Viral.
G Stix (2007). A malignant flame.
St,A Leger,R Hendricks (2012). CD8+ T cells patrol HSV-1-infected trigeminal ganglia and prevent viral reactivation.
Giulio Tarro (2009). Tumor liberated protein from lung cancer and perspectives for immunotherapy.
G Tarro,C Esposito (2011). Emerging viral agents at risk in global health approaches to early diagnosis and prompt therapy.
Giulio Tarro,Antonio Perna,Ciro Esposito (2005). Early diagnosis of lung cancer by detection of tumor liberated protein.
M Thomas,D Pim,L Banks (2010). The role of the human papillomavirus E6 oncoprotein in malignant progression in Viral Oncology.
Richard Thompson,Nancy Sawtell (2011). The herpes simplex virus type 1 latency associated transcript locus is required for the maintenance of reactivation competent latent infections.
Matteo Vergati,Chiara Intrivici,Ngar-Yee Huen,Jeffrey Schlom,Kwong Tsang (2010). Strategies for Cancer Vaccine Development.
L Zerboni,Arvin (2011). Investigation of varicellazoster virus neurotropism and neurovirulence using SCID mouse-human DRG xenografts.
Shanta Zimmer,Donald Burke (2009). Historical Perspective — Emergence of Influenza A (H1N1) Viruses.
Zur Hausen,H (2007). Infections causing human cancer.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Giulio Tarro. 2014. \u201cViral Latency, Molecular Pathogenesis and Malignancy\u201d. Global Journal of Science Frontier Research - C: Biological Science GJSFR-C Volume 14 (GJSFR Volume 14 Issue C3): .

More Citation Formats

Select Citation Style:

Download Citation

Download Article

GJSFR Volume 14 Issue C3
Pg. 55- 60

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

herpesvirus latency oncogenic viruses papillomavirus T antigens

Submission ReceivedAugust 7, 2014
Peer Review Double Blind
Handling Editor
Accepted September 1, 2014
Published September 16, 2014

Version of record

v1.2

Issue date

September 24, 2014

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Score: 101

Country: Italy

Subject: Global Journal of Science Frontier Research - C: Biological Science

Authors: Giulio Tarro (PhD/Dr. count: 0)

View Count (all-time): 187

Total Views (Real + Logic): 4551

Total Downloads (simulated): 2124

Publish Date: 2014 09, Wed

Monthly Totals (Real + Logic):

Month 1: 18 views
Month 2: 56 views
Month 3: 46 views
Month 4: 38 views
Month 5: 34 views
Month 6: 52 views
Month 7: 44 views
Month 8: 27 views
Month 9: 38 views
Month 10: 21 views
Month 11: 37 views
Month 12: 31 views
Month 13: 43 views
Month 14: 16 views
Month 15: 35 views
Month 16: 39 views
Month 17: 42 views
Month 18: 21 views
Month 19: 23 views
Month 20: 41 views
Month 21: 25 views
Month 22: 22 views
Month 23: 32 views
Month 24: 29 views
Month 25: 34 views
Month 26: 20 views
Month 27: 20 views
Month 28: 32 views
Month 29: 21 views
Month 30: 22 views
Month 31: 35 views
Month 32: 28 views
Month 33: 36 views
Month 34: 21 views
Month 35: 40 views
Month 36: 35 views
Month 37: 36 views
Month 38: 38 views
Month 39: 21 views
Month 40: 28 views
Month 41: 26 views
Month 42: 36 views
Month 43: 29 views
Month 44: 23 views
Month 45: 16 views
Month 46: 43 views
Month 47: 31 views
Month 48: 45 views
Month 49: 32 views
Month 50: 38 views
Month 51: 25 views
Month 52: 38 views
Month 53: 34 views
Month 54: 30 views
Month 55: 27 views
Month 56: 26 views
Month 57: 44 views
Month 58: 43 views
Month 59: 36 views
Month 60: 21 views
Month 61: 42 views
Month 62: 31 views
Month 63: 26 views
Month 64: 36 views
Month 65: 15 views
Month 66: 46 views
Month 67: 40 views
Month 68: 39 views
Month 69: 27 views
Month 70: 29 views
Month 71: 41 views
Month 72: 14 views
Month 73: 35 views
Month 74: 34 views
Month 75: 18 views
Month 76: 34 views
Month 77: 16 views
Month 78: 19 views
Month 79: 37 views
Month 80: 16 views
Month 81: 43 views
Month 82: 35 views
Month 83: 38 views
Month 84: 25 views
Month 85: 41 views
Month 86: 15 views
Month 87: 32 views
Month 88: 35 views
Month 89: 39 views
Month 90: 24 views
Month 91: 38 views
Month 92: 37 views
Month 93: 35 views
Month 94: 31 views
Month 95: 31 views
Month 96: 35 views
Month 97: 34 views
Month 98: 32 views
Month 99: 32 views
Month 100: 27 views
Month 101: 26 views
Month 102: 25 views
Month 103: 30 views
Month 104: 43 views
Month 105: 26 views
Month 106: 18 views
Month 107: 20 views
Month 108: 29 views
Month 109: 20 views
Month 110: 18 views
Month 111: 40 views
Month 112: 31 views
Month 113: 24 views
Month 114: 36 views
Month 115: 36 views
Month 116: 29 views
Month 117: 44 views
Month 118: 32 views
Month 119: 36 views
Month 120: 39 views
Month 121: 22 views
Month 122: 17 views
Month 123: 25 views
Month 124: 25 views
Month 125: 22 views
Month 126: 43 views
Month 127: 46 views
Month 128: 34 views
Month 129: 40 views
Month 130: 43 views
Month 131: 25 views
Month 132: 21 views
Month 133: 32 views
Month 134: 22 views
Month 135: 43 views
Month 136: 30 views
Month 137: 22 views
Month 138: 51 views
Month 139: 42 views
Month 140: 50 views

Total Views: 4551

Total Downloads: 2124

2026 Trends

Published Article

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]