Integrating Network Pharmacology and Molecular Docking to Identify the Active Substances and Mechanisms of Chrysanthemum Against Dry Eye
Background: Dry eye is the most common ocular surface disease and is widely treated with chrysanthemum, an herbal medicine known for its anti-inflammatory mechanism. However, the active ingredients, potential targets, and pathways of chrysanthemum in treating dry eye have not been clearly identified. Objective: The objective of this study is to explore the bioactive components and potential mechanism of chrysanthemum on dry eye using network pharmacology and molecular docking. Methods: We used the TCMSP database to search and screen the active ingredients of chrysanthemum and their related targets. Targets associated with dry eye were collected and screened using the Genecards database.
