Bio
Dr. Sujan Narayan Agrawal is a specialist surgeon affiliated with Government Medical College and Hospital, NMDC Ltd, Hyderabad, and Late Shree Baliram Kashyap Memorial Medical College. He is currently a Professor at Late Baliram Kashyap Memorial Government Medical College. He holds an MS(Surgery), FAIS, DH & HM from Late Shree Baliram Kashyap Memorial Medical College.
Educational Journey
Late Baliram Kashyap Memorial Government Medical College
MS(Surgery),FAIS, DH & HM in Department of Surgery • Department of Surgery
Experience
Late Baliram Kashyap Memorial Government Medical College
Professor
2012 - PresentGovernment Medical College
0 - 0Government Medical College and Hospital
0 - 0Affiliations
Late Baliram Kashyap Memorial Government Medical College
Professor
Member since 2012Research
The Development of Vaccines against SARS-CoV-2 Virus. An Overview
The COVID-19 is a zoonotic disease and is caused by the SARS-CoV-2 virus. It is the type of coronavirus. The structural proteins of the virus include the spike (S) protein, membrane (M) protein, envelop protein (E), and nucleocapsid (N) protein. The replication of the virus utilizes all structural proteins. The infection of the host occurs due to the binding of the spike protein to the angiotensin-converting enzyme II (ACE II). It is a positive-sense single-stranded RNA virus belong to the family Coronavridae. The recent outbreak of this disease has caused a lethal pandemic. The previous knowledge of SARS-CoV has helped to develop a vaccine against SARS-CoV-2 also. The humoral and cell-mediated immune response is protective against this infection. The antibody response generated against the S protein, which is the most exposed protein of SARS-CoV, has been shown to protect from infection in mouse models. Multiple studies have shown that the antibodies generated against the N protein of SARS-CoV, are highly immunogenic and abundantly expressed protein during infections.
Deinococcus Radiodurans: The World’s Toughest Bacterium. A Review
Deinococcus Radiodurans is the “world’s toughest bacterium†as per the Guinness book of world record. It is the most radiation-resistant bacterium ever known. It can withstand severe dehydration, cold, vacuum, acid, lack of nutrition, and survive to the radiation dose, a fraction of which is sufficient to kill the human being. The meaning of its name is 'strange berry that withstands radiation.’ This remarkable talent is extensively studied by the biologist and scientist to find out how it survives the extreme life-threatening conditions. This knowledge is being used to find out the means to survive in radiation exposure and also to handle toxic waste.
Glycosylated Haemoglobin (HbA1c): An Indispensible Tool in the Management of Diabetes Mellitus
Diabetes mellitus was known to mankind since antiquity although the name diabetes mellitus was introduced much later. The disease is characterized by elevated blood sugar and estimation of Glycosylated hemoglobin (HbA1c) remains one of the most important and indispensible tool of investigation besides estimation of fasting and post prandiol blood sugar. The glycosylation is the nonenzymetic conjugation of a sugar to amino group of proteins. The authenticity and use of HbA1c in management of diabetes is established by many landmark trials and studies like the Diabetes Control and Complication Trial, (DCCT), UK Prospective Diabetes Study (UKPDS), Standardization of Glycated Hemoglobin testing, National Glycohemoglobin Standardization Programme etc. These studies have developed the methods of HbA1c estimation, the reference range for identification of pre-diabetics and diabetics, and range at which micro and macro-vascular complications occur. If the pitfalls in the estimation of HbA1c is kept in mind its estimation proves a very valuable tool in the management and follow-up of diabetes Mellitus.
