Research
GC-MS Analysis for Structural Identification and Bioactive Compounds in Methanolic Leaf Extract of Mallotus oppositifolius.
The aim of the present study is to investigate the bioactive compounds from the leaf extract of Mallotus oppositifolius using GCMS analysis. The chromatogram showed nine peaks indicating the presence of nine compounds in the extract. The major phytocompounds in the leaf were Glutaconic anhydride with the highest concentration in the extract, 40.19 peak area %, RT 22.686 and molecular formula C5H4O3; 2-Mercaptophenol with 18.23 peak area %, RT 22.068 and molecular formula C6H6 OS. Iso-Valreic and Valeric acids with 12.39,2.53 peak area %, RT 3.676,7.037 and the same molecular formula C5H10 O2 which had been proposed to have anticonvulsant effect in valerian and act as neurotransmitter. Oleamide with the least concentration of 2.15 peak area %, RT 27.959 and molecular formula C18H35NO which could induce sleep in animals, being studied as a potential medical remedy for mood and sleep disorder and cannabinoid–regulated disorder. The phytochemicals in Mallotus oppositifolius could be of therapeutic importance.
Studies on the Medicinal Plant Acalypha Wilkesiana Ethanol Extract Phytocomponents by GCMS Analysis
The ethanolic extract of the leaves of Acalypha wilkesiana plant was studied to find the phytochemical compounds using GCMS analysis. The result of the phytochemical analysis revealed the presence of 12 compounds. Among the 12 compounds, the most abundant were 2-Ethyl-1-hexene with 39.21 peak area %, RT 22.698 and molecular formula C8H16 ; n-Haxadecanoic acid or plamitic acid with 20.92 peak area %, RT:20.92 and molecular formula C16H32O2 and Butane 1,4-diol with 11.58%peak area RT:8.358 and molecular formula of C4H10O2.which demonstrated various medicinal potentials. Therefore the ethanolic leaf extract of Acalypha wilkesiana contain pharmacologically useful active phytochemicals which have effect on progesterone receptors, glucocorticoid receptors, androgen and estrogen receptors with a mild antioxidant and atherosclerotic activity thus could play vital roles in health care programs.
