Bio
Mr. Nwawuba Stanley Udogadi is a dedicated researcher and academic affiliated with the University of Ibadan, Nigeria, where he is based at the Nutritional and Industrial Research Laboratories, Department of Biochemistry, College of Medicine. He also holds connections with Madonna University. His academic journey includes a Bachelor of Science in Biochemistry from Madonna University (2013) and a Master of Science in Biochemistry from the University of Ibadan College of Medicine (2018). Mr. Nwawuba is an active member of the Nigerian Society of Biochemistry and Molecular Biology (since 2016) and the Forensic and Development Centre. His research spans functional dietary supplementation, diabetes mellitus, and forensic science, with notable contributions such as a study on Okara soybeans residue in diabetic male Wistar rats. With 14 publications, 142 citations, an h-index of 6, and an i10-index of 2, he continues to advance knowledge in biochemistry and forensic investigations.
Educational Journey
University of Ibadan College of Medicine
MSc/Biochemistry in Biochemistry • Biochemistry
2018Madonna University College of Medicine
Bachelor of science/Bsc Biochemistry in Biochemistry • Biochemistry
2013Experience
Affiliations
Nigerian society of biochemistry and molecular biology (NSBMB)
Member
Member since 2016Forensic and Development Centre (FORDEC)
Member
Member since 0Research
Functional Dietary Supplementation of Okara soybeans residue on Streptozotocin Induced Diabetes Mellitus in Male Wistar Rats
A poor dietary habit has been demonstrated to be one of the key players in the development of diabetes mellitus, and a diet rich in dietary fiber has been highlighted to be a potent candidate for the management of diabetes mellitus. Therefore, this study is aimed to validate the role of dietary supplementation of okara (soybeans residue) in streptozotocin induced diabetic male Wistar rats. The total of 28 rats between the weight of 100 to 105g, was grouped into four n=7, and this study spanned for a period of 43days. All experimentations were conducted using standard method, and our findings show that the cumulative feed intake of 15% okara diet supplementation was significantly higher p<0.05 particularly from day 29 to day 43 relative to the negative control. After treatment for a period of 43days, 6mg/kg glibenclamide treated group 226.33±6.38 and 15% okara supplemented diet fed group 219.83±5.67 showed a significant increase p<0.05 in body weight relative to the Negative control 161.17±3.60. 15% okara diet supplementation significantly lowered p<0.05 blood sugar levels after treatment relative to after induction similar to 6mg/kg glibenclamide treated group. Glycated hemoglobin, glucose-6-phosphate dehydrogenase, lipid profile (CHOL, TRIG, LDL and HDL), liver function enzymes (AST, ALT, ALP and GGT), kidney function biomarkers (Creatinine, Urea, Sodium and potassium) and antioxidant enzymes (CAT, SOD, GSH, GST and GPX) were all significantly restored within the normal range. Histological observations of the pancreatic, liver, and kidney tissue showed no visible lesion for 15% Okara supplemented diet feeding. Conclusively, we recommend food supplementation with Okara.
