Case Report on Management of Combined Factor V and factor VIII Deficiency during Pregnancy

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dr._kirti_solanki
dr._kirti_solanki
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Dr. Kirti Solanki
Dr. Kirti Solanki
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Dr. Swati Kochar
Dr. Swati Kochar
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Dr. Shweta Choudhary
Dr. Shweta Choudhary
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Dr. Priyanka Gaur
Dr. Priyanka Gaur
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Dr. Krishna
Dr. Krishna

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Case Report on Management of Combined Factor V and factor VIII Deficiency during Pregnancy

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Abstract

Combined factor V and factor VIII deficiency (CF5F8D) is a rare autosomal recessive disorder associated with mild to moderate risk of bleeding tendency. These patients have an increased risk of bleeding after surgical procedures. Pregnant women are at increased risk of having a miscarriage, placental abruption, or post partum hemorrhage. Management of these patients requires the replacement of deficient factors. We are reporting a case of management of a 31-year old second gravida female with combined factor V and factor VIII deficiency, who was transfused with fresh frozen plasma before and during labor to prevent bleeding episodes.

References

11 Cites in Article
  1. Elena Faioni,Gessica Fontana,Giovanni Carpani,Enza D'auria,Giuseppe Banderali,Gianalessandro Moroni,Marco Cattaneo (2003). Review of clinical, biochemical and genetic aspects of combined factor V and factor VIII deficiency, and report of a new affected family.
  2. W Nichols,V Terry,M Wheatley,A Yang,A Zivelin,Ciavarellann (1999). ERGIC-53 gene structure and mutation analysis in 19 combined factors V and VIII deficiency families.
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  4. J Giddings,U Seligsohn,A Bloom (1977). Immunological Studies in Combined Factor V and Factor VIII Deficiency.
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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

dr._kirti_solanki. 2021. \u201cCase Report on Management of Combined Factor V and factor VIII Deficiency during Pregnancy\u201d. Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 21 (GJMR Volume 21 Issue E1): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-E Classification: NLMC Code: WQ 240
Version of record

v1.2

Issue date

March 9, 2021

Language
en
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Published Article

Combined factor V and factor VIII deficiency (CF5F8D) is a rare autosomal recessive disorder associated with mild to moderate risk of bleeding tendency. These patients have an increased risk of bleeding after surgical procedures. Pregnant women are at increased risk of having a miscarriage, placental abruption, or post partum hemorrhage. Management of these patients requires the replacement of deficient factors. We are reporting a case of management of a 31-year old second gravida female with combined factor V and factor VIII deficiency, who was transfused with fresh frozen plasma before and during labor to prevent bleeding episodes.

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Case Report on Management of Combined Factor V and factor VIII Deficiency during Pregnancy

Dr. Kirti Solanki
Dr. Kirti Solanki
Dr. Swati Kochar
Dr. Swati Kochar
Dr. Shweta Choudhary
Dr. Shweta Choudhary
Dr. Priyanka Gaur
Dr. Priyanka Gaur
Dr. Krishna
Dr. Krishna

Research Journals