Demographic and Biological Determinants of Hypertension: Insights about ACE I/D Polymorphism in a population from northeastern Brazil

1
Samuel dos Santos Oliveira
Samuel dos Santos Oliveira
2
Mariane de Oliveira Barreto
Mariane de Oliveira Barreto
3
Pedro Barros Cerqueira
Pedro Barros Cerqueira
4
Poliana Souza Santos Campos
Poliana Souza Santos Campos
5
Dariana Viegas Andrade
Dariana Viegas Andrade
6
Márcio Galvão Oliveira
Márcio Galvão Oliveira
1 Universidade de São Paulo,

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Primary Hypertension is a multifactorial condition and a significant public health concern due to its link with cardiovascular disease. Factors such as obesity, smoking, and genetics contribute to its development. This study examined demographic and biological parameters in hypertensive and normotensive individuals, revealing that ethnicity and family history strongly influence Hypertension risk, particularly among Black participants and those with affected relatives. Hypertensive patients showed higher BMI and waist circumference, with age also contributing to onset. Other parameters, including hip circumference and lipid profiles, were similar between groups.

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No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Samuel dos Santos Oliveira. 2026. \u201cDemographic and Biological Determinants of Hypertension: Insights about ACE I/D Polymorphism in a population from northeastern Brazil\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 25 (GJMR Volume 25 Issue F1): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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December 6, 2025

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English

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Primary Hypertension is a multifactorial condition and a significant public health concern due to its link with cardiovascular disease. Factors such as obesity, smoking, and genetics contribute to its development. This study examined demographic and biological parameters in hypertensive and normotensive individuals, revealing that ethnicity and family history strongly influence Hypertension risk, particularly among Black participants and those with affected relatives. Hypertensive patients showed higher BMI and waist circumference, with age also contributing to onset. Other parameters, including hip circumference and lipid profiles, were similar between groups.

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Demographic and Biological Determinants of Hypertension: Insights about ACE I/D Polymorphism in a population from northeastern Brazil

Samuel dos Santos Oliveira
Samuel dos Santos Oliveira Universidade de São Paulo,
Mariane de Oliveira Barreto
Mariane de Oliveira Barreto
Pedro Barros Cerqueira
Pedro Barros Cerqueira
Poliana Souza Santos Campos
Poliana Souza Santos Campos
Dariana Viegas Andrade
Dariana Viegas Andrade
Márcio Galvão Oliveira
Márcio Galvão Oliveira

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