Effects on DNA and antioxidant system of Anabas Testudineus on Experimental Exposure to a Sublethal Concentration of Methylmercury

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Swetha, S.
Swetha, S.
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Swetha
Swetha
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Pramod Kiran RB
Pramod Kiran RB

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Effects on DNA and antioxidant system of Anabas Testudineus on Experimental Exposure to a Sublethal Concentration of Methylmercury Banner
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Mercury is the most toxic in the organic form like methylmercury (MeHg), with an ability to accumulate in the cells of aquatic organisms like fish. This has been known to adversely affect the functions of almost every aspect of life. This study examined the effects of MeHg exposure on certain antioxidant defences in the liver and muscle of climbing perch (Anabas testudineus) adults and juveniles; the effect on DNA of erythrocytes were also studied. After 15 d of MeHg exposure (87.6 µg L -1 ), the effect of MeHg on DNA of the fish were analysed using comet assay and the activities of SOD (superoxide dismutase), catalase (CAT) and glutathione (GSH) alongwith lipid peroxidation levels (LPO) in the form of TBARS were used as antioxidant markers. The juvenile erythrocytes showed more DNA damage in the form of comets than adults. The activities of SOD significantly increased in all the experimental groups and tissues whereas catalase (CAT) activity increased in adult liver and musclesbut juvenile liver reported a decrease. Glutathione (GSH) levels showed difference in induction depending on the age of the fish with adult liver and muscle showing decrease and juveniles showing significant increase at 15 days of exposure.

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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Swetha, S.. 2026. \u201cEffects on DNA and antioxidant system of Anabas Testudineus on Experimental Exposure to a Sublethal Concentration of Methylmercury\u201d. Global Journal of Science Frontier Research - E: Marine Science GJSFR-E Volume 23 (GJSFR Volume 23 Issue E1): .

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GJSFR Volume 23 Issue E1
Pg. 29- 37
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Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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GJSFR-E Classification: DDC Code: 572.86 LCC Code: QH450.2
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July 25, 2023

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Mercury is the most toxic in the organic form like methylmercury (MeHg), with an ability to accumulate in the cells of aquatic organisms like fish. This has been known to adversely affect the functions of almost every aspect of life. This study examined the effects of MeHg exposure on certain antioxidant defences in the liver and muscle of climbing perch (Anabas testudineus) adults and juveniles; the effect on DNA of erythrocytes were also studied. After 15 d of MeHg exposure (87.6 µg L -1 ), the effect of MeHg on DNA of the fish were analysed using comet assay and the activities of SOD (superoxide dismutase), catalase (CAT) and glutathione (GSH) alongwith lipid peroxidation levels (LPO) in the form of TBARS were used as antioxidant markers. The juvenile erythrocytes showed more DNA damage in the form of comets than adults. The activities of SOD significantly increased in all the experimental groups and tissues whereas catalase (CAT) activity increased in adult liver and musclesbut juvenile liver reported a decrease. Glutathione (GSH) levels showed difference in induction depending on the age of the fish with adult liver and muscle showing decrease and juveniles showing significant increase at 15 days of exposure.

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Effects on DNA and antioxidant system of Anabas Testudineus on Experimental Exposure to a Sublethal Concentration of Methylmercury

Swetha
Swetha
Pramod Kiran RB
Pramod Kiran RB

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