Relationship between COVID-19 and use of Chlorine Dioxide Gas-Releasing Agents in Elementary Schools

1
Yoshinori Kubo
Yoshinori Kubo
2
Takanori Miura
Takanori Miura
3
Kaoru Obinata
Kaoru Obinata
4
Ken Hisata
Ken Hisata
5
Mitsuyoshi Suzuki
Mitsuyoshi Suzuki
6
Eisuke Inage
Eisuke Inage
7
Naotake Yanagisawa
Naotake Yanagisawa
8
Hiromichi Shoji
Hiromichi Shoji
9
Norio Ogata
Norio Ogata
10
Jo Shibata
Jo Shibata
11
Takashi Shibata
Takashi Shibata
12
Toshiaki Shimizu
Toshiaki Shimizu

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Chlorine dioxide has an inactivating effect on various types of viruses in vitro, including severe acute respiratory syndrome coronavirus 2. Therefore, chlorine dioxide gas can be used as a new preventive measure against coronavirus disease 19 (COVID-19). However, no studies have been conducted to investigate the relationship between the incidence of COVID-19 and chlorine dioxide. We retrospectively studied the occurrence of COVID-19 in 164 public elementary schools under the jurisdiction of boards of education located in urban areas in Japan, provided with chlorine dioxide gas-releasing agents or not, from January to March 2022. The odds of developing COVID-19 were lower (odds ratio: 0.934, 95% confidence interval: 0.895-0.975) in schools provided with chlorine dioxide gas-releasing agents than in schools without them. This suggested a relationship between the use of chlorine dioxide-releasing agents and the incidence of COVID-19. Further studies are needed to prove a causal relationship between them.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

Yoshinori Kubo. 2026. \u201cRelationship between COVID-19 and use of Chlorine Dioxide Gas-Releasing Agents in Elementary Schools\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 23 (GJMR Volume 23 Issue F2): .

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Alt text: Study on chlorine dioxide's effectiveness in reducing COVID-19 and its impact on kids' mouth health.
Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification: DDC Code: E
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v1.2

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February 23, 2023

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English

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Chlorine dioxide has an inactivating effect on various types of viruses in vitro, including severe acute respiratory syndrome coronavirus 2. Therefore, chlorine dioxide gas can be used as a new preventive measure against coronavirus disease 19 (COVID-19). However, no studies have been conducted to investigate the relationship between the incidence of COVID-19 and chlorine dioxide. We retrospectively studied the occurrence of COVID-19 in 164 public elementary schools under the jurisdiction of boards of education located in urban areas in Japan, provided with chlorine dioxide gas-releasing agents or not, from January to March 2022. The odds of developing COVID-19 were lower (odds ratio: 0.934, 95% confidence interval: 0.895-0.975) in schools provided with chlorine dioxide gas-releasing agents than in schools without them. This suggested a relationship between the use of chlorine dioxide-releasing agents and the incidence of COVID-19. Further studies are needed to prove a causal relationship between them.

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Relationship between COVID-19 and use of Chlorine Dioxide Gas-Releasing Agents in Elementary Schools

Yoshinori Kubo
Yoshinori Kubo
Takanori Miura
Takanori Miura
Kaoru Obinata
Kaoru Obinata
Ken Hisata
Ken Hisata
Mitsuyoshi Suzuki
Mitsuyoshi Suzuki
Eisuke Inage
Eisuke Inage
Naotake Yanagisawa
Naotake Yanagisawa
Hiromichi Shoji
Hiromichi Shoji
Norio Ogata
Norio Ogata
Jo Shibata
Jo Shibata
Takashi Shibata
Takashi Shibata
Toshiaki Shimizu
Toshiaki Shimizu

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