Bio
Dr. R. T. Kashinath is a Professor of Biochemistry at Subbaiah Institute of Medical Sciences, Shimoga, Karnataka, India. He holds a Ph.D. in Biochemistry (Medical Faculty) and an M.Sc. in Biochemistry, and is a Fellow of the International College of Surgeons (FICS). His research focuses on diabetes mellitus, membrane lipid alterations, and the effects of organosulfur compounds.
Educational Journey
Ph.D. • Biochemistry (Medical Faculty)
M.Sc. • Biochemistry
Experience
Subbaiah Institute of Medical Sciences & Research Center
Professor & Head of Department
0 - Present • BiochemistryBasaveshwara Medical College & Hospital
Professor
0 - 0 • BiochemistryEditors Role
Reviewer
Global Journal of Medical Research
2012 -Affiliations
International College of Surgeons
Fellow
Member since 0Research
Hypolipidemic Effects Of Diaceto-Dipropyl-Disulphide In Alloxan Diabetic Rats
Dyslipidemia is one of the major derrangement observed in type 2 diabetes mellitus which further leads to various life threatening complications. Certain herbal disulphides/thiols are known to cater a solution towards regulation of this diabetes mellitus induced dyslipidemia. It is known that Diallyl Disulphide (DADS), a component of garlic extract possess hypolipidemic activities and may have therapeutic applications, but the metabolite of DADS, acrolein is toxic and poses certain disadvantages. Certain modified /altered disulphides, shown to possess significant hypolipidemic action with lesser toxic effects. In the present study, we tried to establish the hypolipidemic activities of Diaceto-Dipropyl-Disulphide (DADPDS), a synthetic modified disulphide in alloxan diabetic rats. The results show a significant decrease in plasma cholesterol (60%), plasma triacylglycerol (42%), liver tissue cholesterol (41%) and liver tissue triacylglycerol (23%),indicating the usefulness of this modified disulphide in controlling diabetes induced dyslipidemia.
